CELL SURFACE MARKERS DETECTION MARKET ANALYSIS

The global cell surface markers detection market was valued at US$ 5,019.5 Mn in 2022 and is forecast to reach a value of US$ 10,087.6 Mn by 2030 at a CAGR of 9.17% between 2023 and 2030. The global cell surface markers detection market is experiencing strong growth due to the rise in use of cell surface markers in disease diagnostics and rise in prevalence of cancer. Moreover, rise in demand for precision medicine and increasing adoption of flow cytometry in stem cell research is expected to boost the market growth. However, factors such as high cost of instruments and dearth of skilled professionals are expected to hamper the market growth.

Global Cell Surface Markers Detection Market: Regional Insights

Based on geography, the global cell surface markers detection market is segmented into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa.

Among regions, North America is expected to gain highest share in the market over the forecast period due to the increasing prevalence of cancer, rise in use of cell surface markers in diagnostics, and technological advancements in the region. For instance, a paradigm shift in healthcare from disease diagnosis to risk assessment or early diagnosis has increased the use of biomarkers in drug development. According to the American Cancer Society (ACS), cancer continues to be the second most common cause of death in the U.S., after heart disease. In 2023, a total of 1.9 million new cancer cases (about 5,370 cases each day) and 609,820 deaths from cancer are expected to occur (about 1,670 deaths a day) in the United States.

Asia Pacific is also expected to witness robust growth in the global cell surface markers detection market due to the rise in burden of cancer, increase in funding for life science research, and rise in demand for precision medicine in the region. For instance, according to the cancer report by Indian Council of Medical Research (ICMR), India’s cancer cases could increase by 12% in the next five years (2020-2023), with 1.5 million people projected to suffer from the non-communicable disease by 2025, up from 1.39 million in 2020. This in turn is expected to aid in the growth of the global cell surface markers detection market in the region.

Figure 1. Global Cell Surface Markers Detection Market Share (%), by Region, 2023

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Global Cell Surface Markers Detection Market Drivers:

Growing applications in disease diagnostics to boost market growth

One of the key factors expected to augment the growth of the global cell surface markers detection market over the forecast period is the rise in use of cell surface markers in disease diagnostics. For instance, in October 2021, BD Life Sciences-Biosciences and Christian Medical College, Vellore announced the launch of its Center of Excellence (CoE) in flow cytometry for clinical research in India. This CoE will serve as the National Reference Center for clinical diagnostics applications, thereby driving the growth of the market.

Rise in burden of cancer to underpin market growth

Another factor which is driving the growth of the global cell surface markers detection market is the rise in prevalence of cancer around the world. For instance, with the rise in burden of cancer and need for early diagnosis of cancer, the use or demand for cancer biomarkers is also increasing with the rapid pace. According to the World Health Organization (WHO), cancer is a leading cause of death worldwide, accounting for more than ten million deaths in 2020, or nearly 1 in 6 deaths. The most common cancers are breast, lung, colon and rectum and prostate cancers. This in turn is also driving the cell surface markers detection market growth.  

Global Cell Surface Markers Detection Market Opportunities:

Increasing demand for precision medicine across the globe is expected to offer significant growth opportunities for the players in the global cell surface markers detection market. For instance, cell surface markers play an important role in drug discovery and precision or personalized medicine. In October 2017, the National Institutes of Health (NIH) partnered with 11 biopharma companies to launch a 5-year (2017-22), public-private research collaboration to enhance precision medicine approaches to cancer care. The partnership will work to identify, validate, and develop biomarkers that may lead to innovative immunotherapy to treat a wide variety of cancers.

Growing adoption of flow cytometry in stem cell research is expected to offer significant growth opportunities for the players in the global cell surface markers detection market. For instance, flow cytometry is the methodology used for characterizing, analyzing, and isolating stem cells and their derivatives. According to the National Clinical Trial Registry (NCT), as of April 2021, there were about 320 registered clinical trials in various stages of development related to stem cell therapy in Germany. Thus, the increasing stem cell therapy research is expected to increase the demand for flow cytometry during the forecast period.

Global Cell Surface Markers Detection Market Trends:

Development of novel products is a recent trend

Due to increase in use of cell surface markers detection in diagnostics and technological advances, players in the market as well as several governments across the globe are focusing on developing novel/innovative products in the market. Moreover, rise in global disease burden has increased the demand for cell surface markers detection technologies for diagnostics and research applications. Such developments are expected to increase the demand for such technologies, thereby driving the cell surface markers detection market growth.

High usage of flow cytometry is another trend

Flow cytometry is a technique used in cell counting, cell sorting, detecting biomarker, and protein engineering by suspending a cell in a fluid stream and then passing it through a detection apparatus. It is the ideal tool for the identification, characterization, and isolation of stem and progenitor cells for research and the potential clinical use. Flow cytometry is expected to simplify disease analysis, sample separation, and disease diagnosis. Moreover, increasing applications of flow cytometry in clinical research are expected to drive the market growth.

Global Cell Surface Markers Detection Market Restraints:

High cost of instruments to hinder growth of the market

One of the key factors expected to hamper the growth of the global cell surface markers detection market is high cost of instruments. Pharma companies need to invest heavily in instruments, such as flow cytometer and hematology analyzer, to research cell surface markers. For instance, pharma companies are becoming increasingly reluctant to invest in highly sophisticated flow cytometers and hematology analyzer due to the unclear cost-benefit relationship. This limits the entry of small-scale industries and start-ups into the cell surface markers detection market. Therefore, reluctance to invest in such instruments is expected to hinder market growth.

Dearth of skilled professionals to hamper the growth of the market

Another factor which is hampering the growth of the global cell surface markers detection market is the dearth of skilled professionals. For instance, the growing shortage of healthcare professionals (skilled/trained) are also having a great impact on the market, as skilled/trained professionals are required to operate the instrument or devices used in the cell surface markers detection. According to the December 2020 report by the European Commission (EC), almost all of the European Union (EU) countries reported a shortage of healthcare professionals, such as doctors, nurses, and health care assistants between 2019 and 2020.

Figure 2. Global Cell Surface Markers Detection Market Share (%), by Product, 2023

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Global Cell Surface Markers Detection Market Segmentation:

The global cell surface markers detection market report is segmented into Product, Application, and Geography.

Based on Product, the market is segmented into Flow Cytometry, Hematology Analysers, Cell Imaging Systems, Reagents and Kits, and Other Products. Of which, Flow Cytometry Segment is expected to dominate the cell surface markers detection market over the forecast period and this is attributed to the high usage of flow cytometry.

Hematology Analysers Segment is also expected to witness significant growth in the near future and this is owing to the rise in focus on disease diagnosis. Hematology analyzers are used to run tests on blood samples. These analyzers are used to do white blood cell counts, complete blood counts, reticulocyte analysis, and coagulation tests.

Based on Application, the market is segmented into Disease Diagnosis and Identification, Drug Discovery, and Other – Research and Academia Applications. Out of which, Disease Diagnosis and Identification Segment is expected to dominate the market over the forecast period and this is attributed to the increase in disease burden worldwide.

Drug Discovery Segment is also expected to witness significant growth in the near future and this is owing to the increase in focus on drug discovery and development.

Global Cell Surface Markers Detection Market: Key Developments

In July 2021, DiaSorin acquired Luminex Corporation to strengthen its product portfolio in in-vitro diagnostics, and the company will gain access to Luminex's multiplexing technology. This acquisition will also assist DiaSorin in expanding its presence in the United States.

In August 2021, Becton, Dickinson, and Company (BD) launched a new benchtop cell analyzer that brings sophisticated flow cytometry capabilities to laboratories of all sizes. FACSymphony A1 Cell Analyzer is fluorescence-activated cell analyzer that offers advanced research capabilities.

In July 2021, Becton, Dickinson, and Company (BD) announced the commercial release of a new bdbiosciences.com web and eCommerce site, an entirely "reimagined" digital marketplace for flow cytometry designed to provide an enhanced online purchasing experience for users.

In March 2021, F. Hoffmann-la Roche Ltd. announced that it entered definitive merger agreement with GenMark Diagnostics, to fully acquire it and broaden the molecular Diagnostic portfolio.

Global Cell Surface Markers Detection Market: Key Companies Insights

The cell surface markers detection market is highly competitive. This is attributed to the increase in use of cell surface markers detection in diagnostics, as a result, players in the market are focusing on launching novel products in the market.

Some of the key players in the global cell surface markers detection market are Grifols SA, Abbott Laboratories, Sysmex Corporation, Agilent Technologies Inc., Nexcelom Bioscience, Thermo Fisher Scientific Inc., Siemens Healthineers, Nihon Kohden Corporation, F. Hoffmann-La Roche Ltd., Bio Rad Laboratories Inc., Becton, Dickinson and Company (BD), Qiagen NV, Diasorin SpA (Luminex Corporation), Danaher Corporation (Beckman Coulter Inc.), and IVD Medical Holding Limited (Immucor Inc.), among others.

*Definition: Cell surface markers detection refers to the separation and identification of target cells using analytical methods and processes, such as flow cytometry. Cell surface marker analysis through the use of technologies, such as flow cytometry, is expected to simplify disease analysis, sample separation, and disease diagnosis.