Global tooth regeneration market is estimated to be valued at USD 5.10 Bn in 2024 and is expected to reach USD 7.71 Bn by 2031, exhibiting a compound annual growth rate (CAGR) of 6.1% from 2024 to 2031.
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The tooth regeneration market is witnessing positive growth trends. The increasing prevalence of dental caries and other associated dental diseases globally is driving the demand for tooth regeneration treatment methods. Additionally, the rising dental tourism industry in emerging markets is providing impetus to research and development activities in this market. With ongoing clinical trials showing promise, industry players are investing more in technologies leveraging stem cells, biomaterials, and tissue engineering for natural tooth regeneration. This is expected to make tooth regeneration a mainstream treatment option in the near future.
Rising prevalence of dental disorders
The increasing reliance on tooth regeneration solutions for diagnostic purposes has been a key factor boosting the tooth regeneration market. With the rapid rise in chronic and infectious diseases worldwide over the past decade, clinical laboratories have faced significant workload and operational challenges to provide timely diagnoses for patients. The tooth regeneration market is propelled by several key factors, including the escalating incidence of dental disorders, rapid advancements in regenerative medicine, and the expanding elderly population. For instance, according to the WHO Global Oral Health Status Report released in March 2023, oral diseases impact approximately 3.5 billion individuals worldwide, with three-quarters of affected individuals residing in middle-income countries. Globally, an estimated 2 billion people suffer from permanent tooth caries, while 514 million children are afflicted with primary tooth issues. The prevalence of major oral diseases continues to surge globally due to increasing urbanization and shifts in living conditions. Consequently, with a substantial portion of the population affected by oral health problems, there is a growing demand for effective and innovative dental treatments, including tooth regeneration technologies, to combat dental health challenges.
Advancements in regenerative medicine and material science
Advancements in regenerative medicine and material science have opened up pathways for tooth regeneration solutions. Scientists have made significant progress in understanding the biological processes involved in tooth development. Researchers are now able to culture and grow replacement teeth from stem cells in the lab that mimic natural tooth development. This promises to significantly transform dental care by enabling true tooth regeneration and replacement of lost or damaged teeth.
Several regenerative dentistry companies are developing novel proprietary material scaffolds that can support the regrowth of dental tissues from a patient's own cells. These biomaterials are designed to encourage cellular reattachment and neurovascular ingrowth. They promote re-growth of dentin, root and enamel tissues for functional tooth replacement. Successful human trials have been reported where replacement teeth have been regenerated and implanted. For example, a 2021 clinical trial at a U.K. university teaching hospital demonstrated that lab-grown replacement teeth implanted in subjects had fully integrated within the jaw with normal pulp tissue regeneration and blood vessel formation after 12 months.
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