The high cost of treatment procedures is a major factor restraining the growth of the tooth regeneration market. Dental treatments and regenerative procedures such as dental implants, bone grafts, and guided tissue regeneration are often very expensive. According to data from the World Health Organization (WHO), the average cost of a single dental implant in the U.S. ranges from US$ 3,000 to US$ 4,500. Similarly, the average cost of a bone graft procedure is between US$ 2,000 to US$ 5,000. These costs place such advanced treatment options out of reach for many patients, especially those from low and middle-income communities globally. The financial burden of expensive dental treatments discourages many from seeking regenerative care, even if they have severe dental issues. This poses a huge barrier in expanding access to innovative tooth regeneration therapies.
Market Opportunities: Tissue engineering approach for whole tooth reconstruction
Tissue engineering approach for whole tooth reconstruction has the potential to revolutionize the tooth regeneration market. The conventional method of dental implants and bridges have limitations and issues related to biocompatibility. The tissue engineering approach aims to biologically reconstruct a tooth using stem cells and biocompatible scaffolds which can integrate seamlessly within the oral environment. This promising technique closely mimics the natural development of teeth.
The approach involves extracting stem cells from the patient's own dental pulp or oral mucosa. These stem cells are grown in the laboratory and placed onto a porous biodegradable scaffold made of materials like silk, collagen, or hydroxyapatite. This bio-engineered tooth root or crown is then implanted into the empty socket in the jaw bone where it can revascularize and develop innate neural connections. Over a period of six months to a year, the scaffold degrades and gets replaced by the patient's own living dental tissues like dentin, pulp and enamel, eventually forming a fully functional natural tooth.
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