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Advancements in regenerative medicine and material science
Advancements in regenerative medicine and material science have opened up pathways for tooth regeneration solutions. Scientists have made significant progress in understanding the biological processes involved in tooth development. Researchers are now able to culture and grow replacement teeth from stem cells in the lab that mimic natural tooth development. This promises to significantly transform dental care by enabling true tooth regeneration and replacement of lost or damaged teeth.
Several regenerative dentistry companies are developing novel proprietary material scaffolds that can support the regrowth of dental tissues from a patient's own cells. These biomaterials are designed to encourage cellular reattachment and neurovascular ingrowth. They promote re-growth of dentin, root and enamel tissues for functional tooth replacement. Successful human trials have been reported where replacement teeth have been regenerated and implanted. For example, a 2021 clinical trial at a U.K. university teaching hospital demonstrated that lab-grown replacement teeth implanted in subjects had fully integrated within the jaw with normal pulp tissue regeneration and blood vessel formation after 12 months.
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