Global Tissue Plasminogen Activator Market: Key Developments
In July 2021, Boehringer Ingelheim GmbH, a worldwide pharmaceutical company, announced its plan to initiate Phase III part of its Phase II/III TRISTARDS clinical study of alteplase to treat COVID-19 patients with acute respiratory distress syndrome (ARDS). The drug demonstrated a promising safety and effectiveness profile in an interim review of the study, which has completed the exploratory open-label Phase IIb phase with 62 patients.
In May 2021, Biogen Inc., a pharmaceutical company that focuses on neuroscience drugs, and TMS Co., Ltd., a clinical stage biotechnology company, announced that Biogen Inc. exercised its option to acquire TMS-007, a clinical-stage drug for acute ischemic stroke, from TMS Co., Ltd. The acquisition of TMS-007 by Biogen Inc. was based on favorable findings from a Phase 2a research. TMS-007 is a small molecule plasminogen activator with a unique hypothesized mode of action linked to dissolving blood clots and perhaps preventing local inflammation at the site of thrombosis.
In February 2020, Reliance Life Sciences Private Limited, a research-driven organization, launched three biosimilars to the market: interferon beta, reteplase, and human chorionic gonadotropin. Reteplase is a purified version of human tissue plasminogen activator that is used to treat myocardial infarction, ischemic stroke, and pulmonary embolism in the event of an emergency.
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