Global rHu Albumin Market- Restraint
Increasing challenges associated with manufacturing of recombinant human serum albumin are expected to hamper growth of the global rHu albumin market over the forecast period. Production of recombinant human serum albumin (rHSA) is fraught with challenges, particularly in terms of large-scale manufacturing and biosafety. The manufacturing process comprises expression of rHSA from several expression systems, with a focus on the protein's expression levels, downstream processing, cost-effectiveness, and impurity-related safety concerns. A very high expression level is thus the minimal need for commercially producing rHSA at an economically viable level. High recombinant protein deposition may cause unexpected harmful effects in the host, and recombinant protein levels may be reduced via breakdown or aggregation.
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