Key Developments
Major players in the market are focused on gaining product approvals to expand their product portfolio. For instance, in August 2019, AbbVie, a biopharmaceutical company, received the U.S. approval for RINVOQ (upadacitinib), an oral JAK Inhibitor for the treatment of moderate to severe rheumatoid arthritis.
Major institutes and universities are focused on research and development of novel therapies and technologies for the treatment of rheumatoid arthritis. For instance, in August 2019, researchers from the Kaohsiung Medical University, in the paper ‘Next-Generation Sequencing Profiles of the Methylome and Transcriptome in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis’ published in the journal MDPI Journal of Clinical Medicine, revealed a map to the peripheral blood mononuclear cells methylome and found that rheumatoid arthritis genetically associated genes and their interacting targets probably demonstrate differential methylation and differential expression than non-rheumatoid arthritis genetically associated genes.
Moreover, in August 2019, a team of researchers from the University of Groningen and University of Exeter Medical School suggested that Gal-9, a pleiotropic immunomodulatory protein probably promotes immunopathology in rheumatoid arthritis through its stimulatory effect on granulocytes.
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