PLATELET CONCENTRATION SYSTEMS MARKET ANALYSIS

Platelet Concentration Systems MarketSize and Trends

The Global Platelet Concentration Systems Market size is expected to reach US$ 838.4 Mn by 2030, from US$ 424.9 Mn in 2023, at a CAGR of 10.2% during the forecast period. Platelet-rich plasma (PRP) is a non-surgical alternative to cure areas such as orthopedics, sports medicine, dentistry, ear, nose and throat (ENT), neurosurgery, ophthalmology, urology, and wound healing as well as cosmetic, cardiothoracic, and maxillofacial surgery. PRP is an autologous biologic derived from whole blood that is preferentially enriched with platelets and growth factors. It is a commonly used to accelerate the healing of injured tendons, ligaments, muscles, and joints.

While platelets are the primary component of PRP, preparations may also contain other cellular components such as white blood cells (WBCs) and peripheral stem cells. These components play a biological role in the healing process and are provided at concentrated levels in PRP. Thus, PRP may help optimize the conditions for healing of bone and soft tissue.

Global Platelet Concentration Systems Market Drivers:

• Increasing prevalence of target diseases: According to the World Health Organization (WHO), musculoskeletal conditions are the leading cause of disability worldwide with over 1.7 billion people suffering from musculoskeletal conditions. The number of people affected by such conditions is rising rapidly mainly due to aging population and rising obesity levels caused by sedentary lifestyles and unhealthy diets. Similarly, traumatic brain injuries are also on the rise. According to the Centers for Disease Control and Prevention (CDC), it is estimated that every year there are over 2.8 million TBI related emergency department visits, hospitalizations, and deaths in the U.S. alone. Platelet rich plasma therapy has proven effective in speeding up the healing of musculoskeletal injuries and treating neurological conditions like mild TBI and aids in tissue regeneration.
• Rising demand for platelet-rich plasma therapy: The demand for platelet-rich plasma therapy has been steadily increasing over the past few years owing to its potential therapeutic benefits. Platelet-rich plasma therapy involves concentrating platelets from a patient\'s own blood and injecting it in the injured or problem areas to speed up the healing process. It is increasingly being used for treating orthopedic conditions like tendinopathy, ligament sprains, muscle strains, and joint injuries. Various clinical studies have demonstrated the effectiveness of platelet-rich plasma for refractory tendinopathy, knee osteoarthritis and chronic plantar fasciitis among other uses. For instance, according to the study published in 2020 in Journal of American Academy of Orthopedic Surgeons found that the platelet-rich plasma injections to be effective in improving function and reducing pain in athletes with chronic elbow injuries. Another study published in Sports Health journal in 2021 reported that platelet-rich plasma can help reduce symptoms and improve function in athletes with chronic hamstring injuries. The promising results from such studies have helped drive awareness and adoption of the therapy among orthopedic surgeons and sports medicine physicians.
• Increasing adoption of platelet concentration systems in hospitals and surgical centers: The rising demand for platelet concentration systems in hospitals and surgical centers is a significant factor contributing to the growth of the platelet concentration systems market. Platelet-rich plasma (PRP) therapy has gained widespread acceptance in various medical applications such as orthopedics, dentistry, dermatology, and sport medicine in recent times. PRP is derived from platelet concentration systems, which separate and concentrate platelets from whole blood. PRPs deliver a high concentration of autologous platelets and growth factors to injured or damaged tissues for faster healing. They are utilized for treating various orthopedic conditions like arthritis, tendonitis, and ligament injuries. PRP injections help reduce pain and inflammation, and improve the regeneration of connective tissues. Many clinical studies have demonstrated PRPs\' effectiveness in accelerating tissue healing and recovery from injuries. For example, a randomized controlled trial published in 2021 found that PRP therapy after arthroscopic rotator cuff repair surgery led to significant improvements in shoulder function and healing rates compared to controls without PRP.
• Technological advancements in platelet concentration systems: Technological advancements in the field of platelet concentration have enabled significant improvements in platelet-rich plasma therapy. Platelet concentration systems now allow for accurate and rapid concentration of platelets from a patient\'s own blood in an automated, hassle-free manner. This has increased the acceptance of platelet-rich plasma therapy among healthcare professionals by standardizing the preparation process. Fully-automated, next-generation systems streamline the process further by concentrating platelets to a consistent, standardized level with minimal hands-on time. This boosts the efficiency and reproducibility of platelet-rich plasma therapy. Such devices are easy to use by medical practitioners and technicians with minimal training. With their ability to simplify delivery of an advanced treatment option, advanced platelet concentration systems are finding increased acceptance in medical settings ranging from orthopedics clinics to ambulatory surgical centers.
• Growing number of orthopedic and sports injuries: The rising incidence of orthopedic and sports injuries has been a major factor contributing to the growth of the platelet concentration systems market. With people increasingly participating in active recreational sports and physical activities, the risks of injuries such as muscle tears, ligament ruptures, and bone fractures have gone up significantly. According to data from the Centers for Disease Control and Prevention (CDC), over 3.5 million sports and recreation-related injuries are reported annually in the U.S. alone requiring medical care. Sports such as football, basketball, and soccer that involve a lot of jumping, running, and physical contact put athletes at higher risk of such injuries. Additionally, an aging population profile with more people taking part in more risky activities has led to increased joint wear-and-tear and orthopedic issues like arthritis that may need surgical interventions.

Figure 2. Global Platelet Concentration Systems Market Share (%), by Technology, 2023

Global Platelet Concentration Systems Market Trends:

• Increasing preference for automated platelet concentration systems: The preference for automated platelet concentration systems has been steadily increasing among blood banks and hospitals in recent years. This shift towards automation is being driven by the need for higher productivity and standardized results. Automated systems allow for standardization of the entire platelet separation and concentration process from start to finish. They minimize human errors and ensure consistency in product quality by reducing manual interventions. This is important considering platelets must be processed within a strict timeframe and even small inconsistencies can impact patient outcomes. Automated systems also boost production capacities of blood centers. They can process blood donations faster than manual methods, thereby increasing the number of platelet units prepared every day. For example, according to a 2022 report by the American Red Cross, their newest automated blood processing equipment helped increase platelet production by nearly 30% compared to earlier methods. This higher output is valuable as there is always high demand for platelet transfusions from cancer patients and those undergoing complex surgeries and transplants. The productivity gains allow blood banks to meet the needs of more patients.
• Adoption of advanced technologies like centrifugation: The adoption of advanced technologies in platelet concentration systems is having a significant impact on the platelet concentration systems market. Systems that utilize advanced centrifugation techniques are able to process blood plasma much faster and more efficiently than older generation systems. This allows blood collection centers and hospitals to increase their platelet collection capacity without needing to invest in numerous older machines. For example, a modern system that uses progressive segmentation technology can process up to 6 blood donations simultaneously in 30 minutes, whereas older machines may take 1-2 hours for the same number of donations. This higher throughput is appealing to blood banks as it lets them meet the growing demand for platelet transfusions from an aging population with fewer resources. Data from the American Red Cross shows that nearly 28,000 platelet doses are needed every day to treat patients in the U.S., and the demand is expected to increase up to 5% annually over the next decade. Advanced centrifugation technologies help address this demand growth without requiring a proportional increase in facilities and staffing. The ability to extract more platelets faster from each donation also increases the overall yield, allowing valuable resources to be stretched further.
• Membrane separation filters: Membrane separation filters are having a major influence on the platelet concentration systems market. Platelet concentration systems based on membrane separation technology are becoming increasingly popular compared to traditional centrifugation based systems. Membrane separation allows for an easier, more automated process of separating platelets from other blood components without using high speeds. This helps obtain a purer platelet concentrate with higher cell counts. Membrane filtration techniques are able to better maintain the integrity and functionality of the platelets compared to centrifugation. Studies show platelets separated through membranes have higher levels of growth factors and clotting ability. This improves their therapeutic efficacy for indications like bone healing and wound repair. The membrane process is also gentler on the platelets and does not cause the same degree of platelet activation and aggregation seen with centrifugation. Activated platelets are known to have a shorter shelf life. Better preservation of platelet properties is extending the shelf life of membrane derived platelet concentrates.