There are increasing number of clinical trials for use of pertuzumab in combination with other drugs for the treatment of breast cancer . For instance, Helsinki University Central Hospital is undergoing phase III clinical study for adjuvant trastuzumab, pertuzumab, and docetaxel in the treatment of early HER2 positive breast cancer. The study was started in December 2015 and is estimated to complete by June 2023.
Furthermore, increasing number of drug approvals are expected to propel growth of the global pertuzumab market. For instance, in December 2017, the U.S. Food and Drug Administration (U.S FDA) granted approval to PERJETA, a pertuzumab produced by Genentech, Inc. for its use in combination with trastuzumab and chemotherapy as adjuvant treatment of patients with HER2-positive early breast cancer at high risk of recurrence.
Moreover, development of novel anticancer drug delivery technologies is expected to boost growth of the market. For instance, in July 2018, Gentech, Inc., in partnership with Halozyme Therapeutics, Inc., used proprietary ENHANZE drug-delivery technology of Halozyme Therapeutics, Inc., for subcutaneous administration of fixed-dose combination of pertuzumab (PERJETA) and trastuzumab (Herceptin). This study is under clinical phase III trial. ENHANZE technology aids in reducing the need for multiple injections and reduces time required for drug administration.
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