PARP INHIBITOR MARKET ANALYSIS

Market Concentration and Competitive Landscape

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Increased Investment in Precision Oncology Research

There has been a paradigm shift towards targeted and personalized treatment approaches in oncology that has led to significant investments from biopharmaceutical companies, governments, and private foundations to support precision oncology research. Large drug makers have been prioritizing investment in the development of tumor-agnostic as well as tumor-specific targeted therapies. Rapid advancements are being made through immuno-oncology and molecularly targeted agents, including PARP inhibitors, that have enabled treatment of cancers based on their molecular profile rather than site of origin. With improved understanding of cancer genomics and biomolecular underpinnings of the disease, PARP inhibitors are being evaluated across various tumor types harboring defects in DNA repair mechanisms. Research exploring new indications and combination regimens has expanded the use of currently approved PARP inhibitors. This has also aided pharmaceutical companies in maximizing returns on their drug development investments. Several small biotechs are involved in advancing innovative therapeutic candidates in their pipelines. Governments and charities are also making efforts to address gaps in precision cancer research through funding initiatives.