Rituxan drug which is used to treat NHL and had been a front-line treatment regimen, though there has been an increasing rituximab resistance. To overcome this resistance, there has been various R&D practices that will create space in the market. For instance, Roche, Inc. is conducting phase IIIstudy of Gazyva/Gazyvaro in people with previously untreated with diffuse large B-cell lymphoma. . The extension of already marketed drugs such as Velcade as a front-line therapy for mantle cell lymphoma (MCL), Revlimid for maintenance therapy of diffuse large B-cell lymphoma (DLBCL) and Adcetris for CD30 T-cell lymphoma would be further contributing towards the non hodgkins lymphoma treatment market growth. In 2016, the U.S. Government allocated US$ 5.2 billion to the National Cancer Institute (NCI) for cancer research and training purpose.
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