Key Developments
Several institutes are focused on R&D related to nano-silicon drug delivery approaches. For instance, in August 2019, researchers from Icahn School of Medicine at Mount Sinai conducted a clinical trial for gold-silica nanoparticles-based photothermal cancer therapy.
Similarly, in June 2019, researchers from Georgia Institute of Technology reported development of silica spheres of around 200 nanometers in size that can be used for drug delivery to eliminate malignant cells only in certain parts of the body, in the journal Angewandte Chemie International Edition.
In March 2018, researchers from the University of South Australia reported the use of an electrospun composite of poly(ε-caprolactone) fibers and porous silicon nanoparticles as an effective system for the tunable delivery of camptothecin, a topoisomerase inhibitor linked to a cyclodextrin-based polymer to form the investigational anti-cancer drug CRLX101.
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