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Availability of Different Treatment Options
The multiple sclerosis therapeutics sector has witnessed growth over the last couple of decades. What began as a landscape with very limited treatment choices has transformed into a diverse field offering a wide array of FDA approved drugs. These drugs employ different mechanisms of action tailor-made for the specific needs of multiple sclerosis patients during various stages of the disease.
The first wave of multiple sclerosis medications mainly included immunosuppressants that broadly suppress immune activity. While initially revolutionary, these had considerable side effects with long-term use. Subsequently, interferon beta evolved as the first disease-modifying therapy to more selectively target the immune system and show potential neuroprotective benefits. Further research led to improved formulations that are easier to administer.
New oral and injectable drugs like fingolimod, teriflunomide, dimethyl fumarate and antibodies like natalizumab, ocrelizumab and cladribine are used for treating multiple sclerosis. These novel treatments directly address underlying immune pathways incriminated in multiple sclerosis pathology. These achieve superior efficacy outcomes with better safety and tolerability profiles as compared to older immunomodulators. Furthermore, emerging therapies are continually expanding treatment choices at different stages of the disease progression.
This flexibility in choosing optimal therapy significantly impacts treatment adherence and clinical management of the condition. The availability of rich and diversified product portfolio affords both physicians and patients greatly enhanced disease control capabilities.
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