M-RNA SYNTHESIS SERVICE MARKET ANALYSIS

Market Challenges And Opportunities

Global m-RNA Synthesis Service Market- Driver

Increasing Facility Expansion by Market Players

Major companies operating in the global m-RNA synthesis service market are focused on organic growth strategies such as facility expansions, and this is expected to drive growth of the global m-RNA synthesis service market over the forecast period. For instance, in March 2021, Maravai LifeSciences, a global provider of life science reagents and services to researchers and biotech entrepreneurs, expanded its contract development and manufacturing organization (CDMO) capabilities at TriLink BioTechnologies, a division of Maravai LifeSciences, with the launch of its plasmid DNA (pDNA) manufacturing services. TriLink's new plasmid services will provide customers the convenience of a single-source messenger RNA (mRNA) solution, manufactured with Current Good Manufacturing Practice (cGMP) capabilities, from plasmid synthesis through final release testing

Technical and Logistics challenges

Technical and logistics challenges during the synthesis and storage of mRNA therapeutics is expected to hamper the market growth. mRNA vaccines are  unstable at high temperatures that makes packaging and distribution difficult. Long-term storage and delivery of vaccines is important, as governments seeks to vaccinate rural and remote communities. The vaccines have important workflow requirements including storage at very low and consistent temperatures. As a result, manufacturers must have access to reliable cold chain storage, which can be expensive to install, if it is not already in place. Moreover, other challenges associated with mRNAs include intrinsic instability, extremely large size, charge, and high chances of enzymatic degradation.

Therefore, improved vectors or drug delivery systems may help in increasing the wider application of mRNA-based therapeutics and can tackle these restraints.