METABOLOMICS SERVICES MARKET ANALYSIS

Metabolomics Services Market Size and Forecast – 2024 to 2031

The Global Metabolomics Services Market is estimated to be valued at USD 2.85 Billion in 2024 and is expected to reach USD 6.42 Bn by 2031, exhibiting a compound annual growth rate (CAGR) of 12.4% from 2024 to 2031.

Key Takeaways of the Metabolomics Services Market:

• Based on type of technique, the detection techniques segment is expected to contribute the highest share of the market with 52.1% in 2024
• Based on type of service, the targeted metabolomics segment is expected to contribute the highest share of the market with 42.3% in 2024
• Based on application, the drug discovery segment is expected to contribute the highest share of the metabolomics services market with a share of 37.2% in 2024
• North America is expected to top the global market with 39.3% share, followed by Asia Pacific with 25.7% share in 2024

Market Overview:

The increasing applications of metabolomics in personalized medicine, drug discovery and development, biomarker discovery, nutrigenomics, and other fields such as toxicology and cancer are contributing to the growth of this market. The metabolomics services market is witnessing high growth due to rising R&D investments in pharmaceutical and biotechnology companies. Metabolomics helps in understanding pathophysiological mechanisms, as well as in the screening of drug targets, which is driving its increasing adoption in drug discovery and development. Biomarker discovery using metabolomics also plays a vital role in personalized medicine by identifying metabolites that can be used to predict an individual’s response to drugs.

Segmental Insights

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Type of Technique Insights - Advanced Detection Capabilities Drive Detection Techniques Segment

In terms of type of technique, the detection techniques segment is expected to contribute the highest share of the market with 52.1% in 2024 owing to their advanced capabilities to detect a wide range of small molecule metabolites present in biological samples. Detection techniques such as Nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry allow detection of both known and unknown metabolites in minute concentrations without requiring separate extraction and purification steps. NMR provides molecular structural information of metabolites but with low sensitivity compared to mass spectrometry. Mass spectrometry, which can be coupled to gas or liquid chromatography, offers superior sensitivity and ability to detect metabolites right down to femtomole level from complex samples. Continuous technological advancements have enhanced mass spectrometers with features such as high resolution, high mass accuracy, improved ionization methods, and tandem MS capabilities.

Type of Service Insights - Targeted Analysis Leads Metabolomics Services for Targeted Metabolomics Segment

In terms of type of service, the targeted metabolomics segment is expected to contribute the highest share of the market with 42.3% in 2024 on the back of significant demand for targeted analysis of specific metabolites of interest. Targeted metabolomics employs analytical techniques like mass spectrometry and NMR to precisely quantify pre-selected, biologically important metabolites related to metabolic pathways, biomarkers or drug metabolites. It offers an advantage over untargeted methods in delivering quantitative and reproducible results for 20-100 metabolites from biological samples. Common targeted metabolomics applications include biomarker verification studies, pharmacokinetic evaluations to assess drug interactions, metabolic pathway investigations, and clinical metabolite profiling.

Application Insights - Drug Discovery Leads Growth in Application Segment for Disease Diagnosis

In terms of application, the drug discovery segment is expected to contribute the highest share of the metabolomics services market with a share of 37.2% in 2024 owing to widespread adoption across pharmaceutical and biotech companies for disease understanding and therapeutic development. Metabolomics is playing a key role in modern systems pharmacology approaches that integrate multiple -omics techniques to gain a comprehensive view of drug effects in relation to biochemical perturbations linked to diseases. Metabolomics also experiences significant demand from disease diagnosis segment. Metabolic dysregulation analyses through metabolomics are enabling advancements in precision medicine by supporting non-invasive diagnostics, disease sub-typing, assessing disease progression, and treatment responses.

Regional Insights

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North America Metabolomics Services Market Trends

North America's dominance in the metabolomics services market, accounting for a 39.3% share, can be attributed to the strong presence of leading service providers and research institutes actively engaged in metabolomics research in 2024. Growing applications across various end-use industries such as pharmaceutical and biotechnology have further boosted market growth.

Asia Pacific Metabolomics Services Market Trends

The Asia Pacific region exhibits the fastest growth with share of 25.7% in 2024, driven by increasing R&D investments by governments as well as private players. Expanding healthcare and biopharmaceutical industries have augmented demand for specialized metabolomics services to support various analytical requirements. Rising awareness regarding applications in precision medicine is another key factor accentuating market opportunities.

Metabolomics Services Market Outlook for Key countries

U.S. Metabolomics Services Market Trends

The U.S. metabolomics services market is well-established with extensive metabolomics research activities. As chronic diseases rise, the use of metabolomics in research and therapy development is set to grow, driving market expansion. For instance, the Centers for Disease Control and Prevention reports that six in 10 U.S. adults have a chronic disease, and four in 10 have two or more, contributing to over US$ 4.1 trillion in annual healthcare costs. Metabolomics, crucial in identifying biomarkers and understanding disease mechanisms, supports advanced treatments and drug discovery.

China Metabolomics Services Market Trends

China metabolomics services market is growing at a quick pace supported by strong government funding for metabolomics as part of precision medicine initiatives. Shimadzu (China) Co., Ltd., in collaboration with the Dalian Institute of Chemical Physics, Chinese Academy of Sciences, established the Laboratory for Innovative Omics Research to address societal challenges through metabolomics research. This partnership aims to accelerate advancements in the diagnosis of diseases, drug discovery, and other specialized fields like food products.

U.K. Metabolomics Services Market Trends

The U.K. metabolomics services market is growing due to strong collaborations between industry leaders and renowned research institutions. LECO Instruments UK Ltd., a subsidiary of LECO Corporation, announced a training and research collaboration with the Liverpool Training Centre for Metabolomics and the Centre for Metabolomics Research at the University of Liverpool. Renowned globally for their expertise in analytical chemistry and metabolomics applications, these centers will partner with LECO to advance training and research in metabolomics.

India Metabolomics Services Market Trends

The India metabolomics services market is gaining traction due to increasing healthcare investments. In December 2023, the Indian government allocated US$ 20 million for research in metabolomics to enhance disease diagnosis and treatment options.

Market Players, Key Devlopment, and Competitive Intelligence

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Top Strategies Followed by Global Metabolomics Services Market Players

• Established Players: Leading companies in the global metabolomics services market heavily invest in extensive research and development to innovate high-performance products and solution. They focus on developing advanced technologies like AI-assisted metabolomics analysis tools, bioinformatics solutions for large-scale data processing capabilities.
  • For instance, Metabolon Inc. invested over US$ 25 million in R&D last year to launch new targeted and untargeted metabolomics profiling kits using mass spectrometry
• Mid-Level Players: Mid-sized players in the market strive to deliver quality metabolomics services and solutions at competitive prices to attract price-sensitive customers. They collaborate with research institutes and pharmaceutical companies on joint projects involving metabolomics studies of diseases. Such partnerships help mid-players gain technical expertise and industry exposure on a budget.
  • For example, Biocrates Life Sciences AG launched affordable metabolite profiling kits for academic researchers and biobanks
• Small-Scale Players: Emerging small players focus on specific disease areas or bodily fluids barely addressed by large vendors. They leverage cutting-edge technologies to efficiently process complex metabolomics data from niche samples.
  • For instance, Metabologist specializes in plant metabolomics using LC-MS and develops metabolites databases for crops and herbs

Emerging Startups - Metabolomics Services Industry Ecosystem

• Innovative Technologies: Startups are developing AI and machine learning tools to automate metabolite identification from metabolomics datasets. Companies like Metabrain focus on training neural networks on vast reference metabolite libraries to rapidly recognize unknown metabolites in biological samples. Such advanced technologies could help drive down costs and speed up metabolomics workflows.
• Sustainable Solutions: Some startups offer green chemistry approaches for sample preparation in metabolomics studies. Bioprofile develops enzymatic extraction kits that replace toxic organic solvents with cellulase enzymes, contributing to more sustainable metabolomics research. Their solutions help reduce hazardous waste generation in labs.
• Market Contribution: Emerging companies are entering niche segments often overlooked by established players. For instance, PhytoMetrix specializes in plant metabolomics, focusing on fruits, and provides comprehensive metabolite databases for specialty crops and orchards. Their metabolite identification services support research on niche fruits, aiding in the development of functional foods and enhancing crop quality.

Key Developments:

• On May 30, 2024, Metabolon, Inc., a leader in metabolomics solutions, introduced a 4-week turnaround for Global Discovery Panel projects of up to 2,000 samples, addressing the needs of commercial pharmaceutical markets. This enhancement supports faster R&D by providing timely insights from biological fluids like plasma, urine, and serum.
• On January 26, 2023, CosmosID, a leader in high-resolution microbiome analysis, introduced metabolomics services to support multi-omics research. Combining metagenomics, metatranscriptomics, and metabolomics, this approach offers detailed insights into microbial composition, gene expression, and metabolite production. The service aims to deliver actionable data for advancing microbiome research.
• In July 2021, Thermo Fisher Scientific, a global leader in serving science, offering innovative technologies, analytical instruments, and laboratory services, collaborated with University of California, U.S to establish the Center of Excellence in Clinical Metabolomics, advancing innovations and standardization in metabolomics research
• In April 2021, BioMérieux, a pioneer in in-vitro diagnostics, which specializes in microbiology, immunology, and molecular diagnostics, received CE Marking for VITEK MS PRIME, a cutting-edge MALDI-TOF mass spectrometry system for rapid microorganism identification, streamlining microbiology workflows

Market Report Scope

Market Dynamics

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Metabolomics Services Market Driver - Increasing prevalence of chronic diseases

The global burden of chronic diseases has been rising steadily and is posing huge challenges to healthcare systems worldwide. Chronic conditions such as cancer, diabetes, and cardiovascular diseases have become the major causes of mortality with changing lifestyles and dietary patterns. Metabolic research plays a crucial role in better understanding the pathogenesis of many chronic illnesses and developing targeted treatment approaches. Metabolomics can help identify novel biomarkers for early disease detection as well as monitor disease progression and treatment effectiveness. Various metabolic profiling tools are being utilized by researchers to gain mechanistic insights into diseases. In May 2021, according to GLOBOCAN 2020, there were approximately 19.3 million new cancer cases and 10 million cancer-related deaths worldwide in 2020.

Metabolomics Services Market Challenge - High costs associated with metabolomics technologies

One of the major challenges being faced by the global metabolomics services market is the high costs associated with metabolomics technologies. Metabolomics research requires expensive instruments like mass spectrometers, NMR spectrometers, and chromatography equipment. These instruments are highly sophisticated and can cost anywhere between hundreds of thousands to millions of dollars depending on the technology. Additionally, the consumables, reagents and kits used for sample preparation and analysis are also expensive. The maintenance of these instruments also requires huge costs. These exorbitant costs of technologies pose significant barriers for small and medium research organizations to establish core metabolomics facilities of their own. The high capital expenditure constraints the expansion of metabolomics research facilities.

Metabolomics Services Market Opportunities - Development of personalized medicine approaches for market

One of the major opportunities for the global metabolomics services market is the development of personalized medicine approaches. Metabolomics helps to facilitate a shift towards personalized medicine by enabling an understanding of individual metabolic phenotypes. Metabolomics can help develop metabolic biosignatures which can be used to predict disease risk, diagnose patients, monitor treatment response and develop targeted therapies. The potential of metabolomics to deliver personalized preventive interventions and treatments based on an individual's metabolic profile offers a huge market opportunity.

Analyst Opinion (Expert Opinion)

• The global metabolomics services market is expected to witness significant growth over the forecast period driven by increasing R&D investment in drug discovery and development. The growing adoption of metabolomics approach for biomarker identification is further expected to propel the market growth. Additionally, rising prevalence of chronic and infectious diseases will fuel the demand for metabolomics services from pharmaceutical and biotechnology companies.
• However, the market growth can be restrained by the high capital investment required for establishing metabolomics core facilities. Also, shortage of skilled professionals and lack of advanced infrastructure in emerging markets poses a challenge.
• The North America region currently dominates the market and is expected to continue its dominance led by well-established biotech industry and major metabolomics services providers in the U.S. However, the Asia Pacific region is likely to witness the highest growth owing to rising healthcare expenditure, growing biomedical industry, and increasing R&D investments by market players looking to tap the opportunities in emerging Asian countries.
• Metagenomics application area is anticipated to register fastest growth over the forecast period. Metabolomics is increasingly being utilized in metagenomics research for studying microbial metabolites and interactions, which will boost the metabolomics services adoption.

Market Segmentation

• By Type of Technique Insights (Revenue, USD Bn, 2019 - 2031)
• • Detection Techniques
    • Nuclear Magnetic Resonance Spectroscopy (NMR)
    • Mass Spectrometry (MS)
  • Separation Techniques
    • Gas Chromatography (GC)
    • Capillary Electrophoresis (CE)
    • Liquid Chromatography (LC)
    • Others (Supercritical Fluid Chromatography, Ion Mobility Spectrometry, etc.)
• By Type of Service Insights (Revenue, USD Bn, 2019 - 2031)
• • Targeted Metabolomics
  • Untargeted Metabolomics
  • Metabolite Profiling
  • Biomarker Discovery
  • Other Services
• By Application Insights (Revenue, USD Bn, 2019 - 2031)
• • Drug Discovery
  • Toxicology Testing
  • Biomarker Discovery
  • Nutritional Research
  • Disease Diagnosis
  • Other Applications
• By End User Insights (Revenue, USD Bn, 2019 - 2031)
• • Academic and Research Institutes
  • Pharmaceutical and Biotechnology Companies
  • Contract Research Organizations (CROs)
  • Diagnostic Laboratories
  • Others
• Regional Insights (Revenue, USD Bn, 2019 - 2031)
• • North America
    • U.S.
    • Canada
  • Latin America
    • Brazil
    • Argentina
    • Mexico
    • Rest of Latin America
  • Europe
    • Germany
    • U.K.
    • Spain
    • France
    • Italy
    • Russia
    • Rest of Europe
  • Asia Pacific
    • China
    • India
    • Japan
    • Australia
    • South Korea
    • ASEAN
    • Rest of Asia Pacific
  • Middle East
    • GCC Countries
    • Israel
    • Rest of Middle East
  • Africa
    • South Africa
    • North Africa
    • Central Africa
• Key Players Insights
• • Agilent Technologies
  • Thermo Fisher Scientific
  • Waters Corporation
  • Bruker Corporation
  • Merck KGaA
  • PerkinElmer
  • Danaher Corporation
  • Bio-Rad Laboratories
  • Shimadzu Corporation
  • Human Metabolome Technologies, Inc.
  • Metabolon, Inc.
  • LECO Corporation
  • Scion Instruments
  • DANI Instruments S.p.A.
  • GL Sciences