MEPERIDINE (DEMEROL) MARKET ANALYSIS

Market News

Global Meperidine (Demerol) Market: Key Developments

The increasing research and development activities by key market players can drive growth of the global meperidine (Demerol) market over the forecast period. For instance, according to an article published by European Heart Journal on October 14, 2021, a study was conducted on 66 patients, to study the prophylactic role of meperidine in avoiding radial artery spasm during transradial cardiac interventions. The patients were divided into two groups. Group A had 42 patients while group B had 24 patients. Patients were randomized to either meperidine 0.25mg administration (Group A) or normal saline (Group B) intravascular administration. 10 minutes before the beginning of the procedure, as standard prophylactic measures against spasm, both groups received verapamil 5mg and nitroglycerin 100μg, after sheath introduction in the radial artery. Artery spasm was assessed clinically by the difficulty in advancing or exchanging catheters. It was concluded that meperidine low dose administration before radial artery catheterization shows positive results in preventing spasm and reducing patient related discomfort.

According to an article published by Iraqi Journal of veterinary Sciences on December 25, 2022, a study was conducted on rats to understand meperidine pharmacokinetics and impact on it due to tramadol co-administration. The findings showed that meperidine and tramadol showed synergistic action. An alteration in meperidine pharmacokinetics could improve meperidine effectiveness in the rats.

According to an article published by journal The Horizon of Medical sciences on July 2021, a comparison of intravenous ketamine, meperidine, and dexamethasone to prevent postoperative shivering in patients undergoing general anesthesia was evaluated. The results showed that all three drugs are effective in preventing postoperative shivering. There was no difference between these medications in prevention of postoperative shivering.

According to an article published by Journal of Investigative Surgery on February 8, 2021, the effectiveness of Caudal Block (CB) with low doses of dexmedetomidine and meperidine in transrectal prostate biopsy were studied. A Study was conducted on total 68 patients with mean age of 65 years. The pain levels of the patients were determined using Numeric Rating Scale (NRS) scores to evaluate the effectiveness of CB. Preoperative and postoperative post void residual urine volumes were also calculated. It was concluded that the combination of dexmedetomidine and meperidine for CB in transrectal ultrasound-guided prostate needle biopsy provided quality analgesia for the patient and prevented the development of postoperative urinary retention.