The global measles, mumps, and rubella vaccines market is segment on the basis of geography into North America, Europe, Asia Pacific, Latin America, Africa, and Middle East. According to the Pan American Health Organization (PAHO), 2017, measles and rubella have been eliminated from the Americas region, however, the challenge lies in preventing the outbreak. However, according to a report by CDC’s National Center for Immunization and Respiratory Diseases (NCIRD), in 2014, the U.S. recorded 667 number of measles cases from 27 states, which was the highest number of cases since measles elimination was documented in the U.S. in 2000. This states that the vaccine programs were unsuccessful in preventing the outbreak of the disease.
Key manufacturers in the measles, mumps, and rubella vaccine market are focusing on launching new vaccines, in order to enhance their share in the market. According to Access to Medicine Foundation index, 2017, vaccine market is dominated by four major players, collectively referred as 'big four': GSK, Merck & Co., Inc., Pfizer, and Sanofi. Big four contribute to 80% of the global vaccine revenue. Players vary significantly by portfolio and pipeline size. Three of the four companies have larger pipelines than Merck & Co., Inc. or Pfizer. In March 2107, GSK’s measles, mumps, and rubella vaccine for indication of measles, mumps, and rubella prophylaxis was in phase III trial, which is expected to commercialize in the forecast period of 2017 to 2025. Priorix and Priorix Tetra Measles, mumps and rubella vaccine of GSK are expected to lose their patents in 2019 in the U.S. Some small players such as Daiichi Sankyo and Takeda are focusing on launching vaccines for MMR in regional markets. For instance, Daiichi Sankyo’s VN-0102/JVC-001 is measles, mumps, and rubella vaccine in phase I clinical trials as of May 2016.
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