Global inflammatory bowel disease market is estimated to be valued at USD 22.31 Bn in 2024 and is expected to reach USD 30.10 Bn by 2031, exhibiting a compound annual growth rate (CAGR) of 4.4% from 2024 to 2031.
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Increasing prevalence of Crohn’s disease and ulcerative colitis across the can drive the market growth. As per the National Center for Biotechnology Information (NCBI), Crohn's disease cases are more common in northern parts of the world such as North America and Northern and Western Europe. While ulcerative colitis cases are more common in the southern parts of the world such as South America and the Middle East. Rising awareness regarding the disease symptoms and management options available can also drive the market growth. However, high costs associated with branded drugs can hamper the market growth during the forecast period.
Rising prevalence of Crohn's disease and ulcerative colitis
The rising prevalence of Crohn's disease and ulcerative colitis globally is one of the major factors fueling the growth of the inflammatory bowel disease (IBD) market. These conditions cause chronic inflammation and ulcers in the digestive tract. According to the latest data from the Crohn's & Colitis Foundation, over 3 million Americans currently suffer from IBD. In Europe as well, nearly 2.5-3 million new cases are reported each year as per the European Federation of Crohn's & Ulcerative Colitis Associations. The increasing disease incidence can be attributed to changing lifestyle patterns and diets around the world. While genetics play a role, experts indicate environmental triggers like smoking, lack of breastfeeding, and low fiber intake as primary causes behind the disease growth. As per the World Health Organization, Canada and North American countries have witnessed the highest surge, with the incidence rates reaching over 200 per 100,000 population in the last decade alone. The growing morbidity demonstrates the urgent need for medications and overall disease management.This rising prevalence has created considerable commercial opportunities in the IBD market globally. Pharmaceutical companies are investing heavily in R&D to develop novel biologics, biosimilars, and small molecules effective for both induction and maintenance of remission. Some of the latest therapies approved include JAK inhibitors, IL-23 and IL-12/23 antibodies catering to the unmet needs. Further, demand for non-drug therapeutics like enteric-coated preparations, nutrition supplements is also growing. The increase in product pipeline and diversity of treatment options available today are positively impacting the revenue potential of this market. Growing patient pool, changing reimbursement programs supporting Biologics in various countries, and emergence of pharma companies in developing regions like Asia Pacific and Latin America will propel the IBD market to greater heights in the next 5 years. However, ensuring drug affordability and access will play a crucial role in maximizing this potential, especially in lower resource settings.
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Rising healthcare spending and access to advanced treatments
Rising social and economic burden of inflammatory bowel diseases has led to greater allocation of healthcare budgets towards effectively managing these conditions. Improved access to healthcare facilities combined with higher disposable income levels have enabled patients to seek and afford superior medical care. This evolving treatment landscape can offer lucrative opportunities for companies offering biologics and other novel drug classes. While still primarily used in refractory cases or as rescue therapy due to their high costs, biologics targeting factors like TNF-alpha and integrins have revolutionized management of Crohn's disease and ulcerative colitis. Constant innovations can further increase convenience of administration through devices like pen injectors, thus improving patient adherence as well. The complex interplay of encouraging reimbursement schemes, enhanced patients' welfare initiatives and the promising drug development pipeline are expected to significantly elevate overall spending on advanced gastrointestinal therapies globally.
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