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Growing Adoption of Combination Therapies
There has been increased use of combination immunotherapies aimed at targeting multiple immune checkpoints during cancer treatment. Combination therapies have emerged as a promising strategy to optimize clinical response rates and combat resistance to monotherapies. Early studies have shown that combined blockade of PD-1 and CTLA-4 improves survival outcomes over single-agent therapies for many cancer types. Combination regimens are also more effective than sequential therapies in eliciting durable anti-tumor responses. With initial positive clinical data, combination strategies are expected to become first-line options for cancer indications. Drug manufacturers are actively pursuing combination therapies through collaborations and pipeline expansion focused on dual or triple immune checkpoint inhibitors. The clinical benefits of combination immunotherapies over single agents drives physicians and patients to increasingly adopt such treatment approaches.
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