Immune check activators market mainly in pre-clinical trial stage, with rampant growth projected post-commercialization
Inovio Pharmaceuticals—a major player in the industry—has three different DNA immune activators in pre-clinical and clinical studies. Inovio’s DNA-based IL-12 immune activator enhanced antigen-specific T cell immune responses from its HIV DNA vaccine, PENNVAX.
Inovio, testing DNA IL-28B in combination with its multi-antigen hepatitis C DNA immunotherapy, INO-8000, is in phase I study in HCV patients.
Inovio’s DNA-based IL-33 immune activator, in combination with a DNA immunotherapy targeting HPV-16, led to rapid and complete tumor regression in mice. The approval and launch of these products would position the global immune check activators market on high growth trajectory.
GlaxoSmithKline Pharmaceuticals and Genentech are much focused on investment for research and development in immune activation methodology
Regional segmentation of the immune check activators market by Coherent Market Insights comprises North America, Europe, Asia Pacific, Latin America, Middle East, and Africa. North America accounts for the largest share in the global market, mainly due to presence of major players and adoption of advanced research technologies in countries such as the U.S. and Canada. Increase in cancer prevalence globally is the prominent factor projected to boost growth of the market of immune check activators during the forecast period (2016–2024). Increase in government support and funding towards clinical trials on development of new drugs for cancer therapy also inspires the investigators in developing novel drugs.
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