Immune Anti-Inhibitor MarketSize and Trends

Immune Anti-Inhibitor Market Drivers

According to Centers for Disease Control and Prevention (CDC), 2016, an estimated 1 in 5 people with haemophilia A and about 3 in 100 people with haemophilia B develop inhibitors (antibodies). Moreover, patients suffering from Von Willebrand Disease (VWD) type 3 are also at a risk of developing inhibitors. According to National Haemophilia Foundation (NHF), haemophilia A occurs in 1 in 5,000 people and is four times as common as haemophilia B, which supports growth of the immune anti-inhibitors market. Ongoing research and development of different therapies for haemophilia with inhibitors are expected to boost growth of the global immune anti-inhibitor market. For instance, Roche is working on monoclonal antibodies for treatment of haemophilia with inhibitors. In June 2017, Roche’s emicizumab (Hemlibra) showed positive results in Phase III studies in haemophilia A with inhibitors. The U.S. Food & Drug Administration (FDA) approved Emicizumab (Hemlibra) once – weekly subcutaneous therapy for haemophilia A with inhibitors in September 2017. Emicizumab is a monoclonal antibody designed to facilitate blood clotting process by combining factors IXa and X. Moreover, the Center for Disease Control and Prevention (CDC) is examining the etiology of the haemophilia with inhibitors, which could help in development of novel therapies to boost growth of the immune anti-inhibitor market. Pipeline for haemophilia with inhibitors is also promising as few of the manufacturers are working on novel therapies for the condition. One such organization Catalyst Biosciences has a Factor VIIa marzeptacog alfa (activated) in the clinical trials for haemophilia A or B with inhibitors. Moreover, Bioverativ Inc., a Sanofi S. A.'s subsidiary has FVIIIa mimetic bispecific antibody under studies for haemophilia A with inhibitors. Multiple products are pipeline which are expected to receive approval over the forecast period, this in turn is projected to boost growth of the immune anti-inhibitor market over the forecast period.

Immune Anti-Inhibitor Market Insights

Government organizations and agencies are engaged in providing support to patients suffering from haemophilia with inhibitors by increasing the awareness of the disease. For instance, the National Haemophilia Foundation (NHF) Inhibitor Education Summits help in spreading awareness and information about the disease condition. Moreover, the Haemophilia Federation of America’s Helping Hands Program offers financial assistance to financially unstable population for attending national and state bleeding disorder educational meetings; travel for necessary medical procedures, surgeries and second opinions; and tutoring or education-related expenses.