Global Human DNA Vaccines Market: Dynamics
The inherent benefits of the human DNA vaccines over the other vaccines is the major factor contributing to driving the growth of the market. Inherent benefits of DNA vaccines, such as cost, efficiency, safety, reduced time for production, more stability especially when necessary to be transported, and the easy inclusion of immunostimulatory sequences contributes to drive the market growth.
Moreover, the positive results of the clinical trials owing to the advancement in biotechnology and research studies are imposing a positive outlook on the growth of market. For instance, in August 2021, India approved world’s first DNA COVID-19 Vaccine ‘ZyCoV-D’ by Zydus Cadila. The three-dose ZyCoV-D vaccine prevented symptomatic disease in 66% of those vaccinated, according to an interim study quoted by the vaccine maker Cadila Healthcare. The firm plans to make up to 120 million doses of India's second home-grown vaccine every year.
Furthermore, the increasing prevalence of infectious diseases such as cancer, hepatitis, and others besides the increasing number of resistant pathogens are some factors that will drive the global human DNA vaccines market growth.
Additionally, the spread of COVID 19 pandemic has caused an increase in the efforts to produce safer vaccines to treat the disease which will drive the DNA vaccine market growth. For instance, according to a report published by Medical Life Sciences, in February 2021, there were 250 vaccines in development to combat the coronavirus pandemic out of which 181 were in preclinical development, while 69 were undergoing clinical evaluation. Among the vaccines in clinical evaluation 10 vaccines were DNA vaccines. Furthermore, in August 2021, INOVIO an American biotechnology company has received authorization to conduct phase III efficacy trial of its COVID-19 DNA vaccine candidate, INO-4800 due to promising results of the initial trials. Composed of a precisely designed DNA plasmid, INO-4800 is injected intradermally followed by electroporation using a proprietary smart device delivering the DNA plasmid directly into the cells in the body and is intended to produce a well-tolerated immune response. INO-4800 is the only nucleic-acid based vaccine that is stable at room temperature for more than a year, at 37°C for more than a month, has a five-year projected shelf life at normal refrigeration temperature and does not need to be frozen during its transport or storage.
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