Global Hemorrhagic Shock Treatment Market - Regional Analysis
Among region, North America is estimated to hold a dominant position in the global hemorrhagic shock treatment market over the forecast period, owing to increasing research and development in treatment for hemorrhagic shock. For instance, on March 25, 2023, John Wiley & Sons, Inc published an article explaining polyethylene glycol 20,000 is a solution that can be used in "minimum resuscitation", which can advantageously reduce the logistical burden in severe combat conditions. The mechanism of PEG-20 K targets the microvasculature and the unique solute can exit the vasculature into the interstitial space, but remains cell impermeable and too large to pass through the capillaries, providing an oncotic force to prevent cell swelling and maintain microcirculation. In a study comparing small volumes of fluids given in hemorrhagic shock, a preclinical study in all pigs given PEG-20 K survived compared to less than 20% of pigs given other fluids (whole blood and hetastarch). PEG-20 K restored mean arterial pressure, intravascular volume, and capillary perfusion.
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