RARE DISEASE DRUGS MARKET COMPETITIVE ANALYSIS ANALYSIS

Leading Companies

Competitive Analysis of top 10 organizations in the global rare disease drugs market

Top 10 organizations in the global rare disease drugs market in 2016, based on the 2016 revenue include:

• Novartis AG
• Hoffmann-La Roche Ltd.
• Celgene Corporation
• Bristol-Myers Squibb Company
• Shire plc
• Pfizer, Inc.
• Sanofi S.A.
• Bayer
• Alexion Pharmaceuticals, Inc.
• Biogen, Inc.

1. Novartis AG is a global pharmaceutical organization with a diverse product folio ranging from drug therapies for cancer treatment to ophthalmic products. The company operates business through Innovative Medicines Division, which consists of oncology business unit and Novartis pharmaceutical business units. Innovative medicines Oncology division offers products for oncology diseases and rare diseases, and pharmaceutical business consists of ophthalmology, neuroscience, immunology and dermatology, respiratory, cardio-metabolic, and established medicines. Novartis lost patent protection for its orphan drug Gleevec for the treatment of chronic myeloid leukemia (CML) in 2015 and Sun Pharma brought out generic Gleevec in 2016 hampering the sales of Novartis for Gleevec.
2. Celgene Corporation specializes in therapies for cancer treatment and inflammatory diseases which includes drugs such as Revlimid, Pomalyst, and Otezla. The company currently is concentrated on expanding the indication range of the present therapies and has a robust pipeline for oncology conditions. For instance, Revlimid (lenalidomide), in phase III clinical trials for diffuse large B-cell lymphoma, indolent lymphoma, and follicular lymphoma. Furthermore, the company has developed its own target-identification and drug-discovery technology platforms which enable the company to proceed rapidly from target identification and validation to lead identification and optimization.
3. Shire Plc. became global leader in orphan drug products category (excluding oncology products) in year 2016 and grossed almost US$ 11 billion. The company acquired Baxalta in 2016, and its three therapeutic segments namely hematology, immunology, and oncology. Shire Plc. is also focused on providing therapies for rare diseases as it invested US$ 1.4 billion in research and development. The company had 37 therapies in research and the pipeline has further been strengthened by acquisition of Dyax and Baxalta in 2016.