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Heightened threat from new virus strains
Foot and mouth disease virus has a high mutation rate which allows new variants to evolve constantly. Emergence of novel strains that the existing vaccines may not offer protection against can pose a serious challenge. In recent years, unusual outbreaks caused by atypical FMD virus strains have been reported from parts of Asia, Africa and South America. For example, a virus type O pandemic strain affected huge cattle herds in countries like South Korea, Vietnam and Taiwan in 2010-2011 despite vaccination. Similarly, an unusual topotype of type A virus caused repeated epidemics in Middle East and North Africa since 2009 even in vaccinated cattle. Containing such rapidly evolving strains with cross-border spread capabilities requires continuous vaccine development and shortening of response times. This evolving epidemiological pattern boosts the need for enhanced surveillance of FMD viruses to design vaccines matching the circulating field strains more precisely.
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