Global Epo Biomarkers Market: Drivers
The epo biomarkers market is expected to witness significant growth over the forecast period, owing to increasing launch and adoption of erythropoietin alfa in cancer patients who are suffering from anemia. For instance, in November 2018, Pfizer launched epoetin alfa biosimilar — Retacrit — at 33% discounted rate than the original drug in the U.S. for treatment of anemia caused by chronic kidney disease and chemotherapy.
Furthermore, increasing prevalence of ESRD, which causes kidney failure and is often fatal is expected to boost the market growth. According to the U.S. Renal Data System Annual Data Report of 2016, over 660,000 people in the U.S. were treated for kidney failure or ESRD. Out of these, 468,000 were dialysis patients and over 193,000 had a functioning kidney transplant.
Global Epo Biomarkers Market: Restraints
A major restraining factor for the epo biomarkers market growth is the over-production of red blood cells due to over-expression of epo biomarkers, which leads to absolute polycythemia and other conditions. Overproduction of epo may be an adaptive response associated with conditions that produce tissue hypoxia such as living at high altitude, chronic obstructive pulmonary disease, cyanotic heart disease, and sleep apnea. According to an article published in Biospace Journal in 2015, in the U.S. between 40% and 90% of cancer patients suffer from chemotherapy-induced anemia. Use of epo in cancer patients that suffer from chemotherapy-induced anemia was restricted by the Food and Drug Administration (FDA) due to increasing adverse events including decreased survival and increased risk of tumor progression and recurrence.
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