DNA AND RNA SAMPLE PREPARATION MARKET ANALYSIS

Market Challenges And Opportunities

Global DNA and RNA Sample Preparation Market - Driver

Prevalence of infectious diseases across the world

The cases of infectious diseases are constantly rising worldwide. Due to this global burden of infectious diseases, the need for accurate, reliable and newer detection technologies are required. Hence, this factor can drive growth of global DNA and RNA sample preparation market. For instance, according to data reported by the World Health Organization, on April 21, 2023, a total of 1.6 million people died from Tuberculosis (TB) in 2021. Worldwide, TB is the 13th leading cause of death and the second leading infectious killer after COVID-19. In 2021, an estimated 10.6 million people fell ill with tuberculosis (TB) worldwide. Only about 1 in 3 people with drug resistant TB received treatment in 2021.

Increasing launches of new products

Rapid diagnosis and treatment of infectious disease is necessary due to increased burden of infectious diseases. Hence, key market players are focused on receiving approvals of newer diagnostic kits. For instance, on November 30, 2022, Mylab discovery solutions, India based biotechnology company received Central Drugs Standard Control Organization (CDSCO) and Indian Council of Medical Research (ICMR) approval for its product PathoDetect. It is a Real-Time Reverse Transcription Polymerase Chain Reaction (RT-PCR) based kit that allows automated testing of multiple samples within 2 hours. It is a TB detection kit, which can simultaneously detect multiple drug resistance to rifampicin and isoniazid in single test.

Global DNA and RNA Sample Preparation Market: Restraint

High cost of DNA & RNA sample preparation methods

DNA & RNA sample preparation is the first and essential step of any biological procedure. However, the materials and the labor work required in preparation of sample is very costly. Hence, it results into increasing overall cost of process. Also, available kits have limited throughput so scaling it to higher sample requires automation. The reagents used are also very costly. For instance, according to article published by BMC Genomics on August 24, 2022, about 80% of the total costs of genomic sequencing occur prior to sequencing during DNA & RNA extraction.

To counter balance the restrain, government funding should be given to promote research and development activities in biotechnological fields.

Problems with RNA sample handling

RNA preparation and handling is the challenge faced by diagnostic laboratories. According to an article published by International Journal of Molecular Sciences, on January 20, 2023, obtaining a full length and high quality RNA can be challenging. This is because, while working in the environment it should be free from RNase. Sample should be frozen immediately after collection. Logistics problems can also cause a delay in sampling hence compromising quick tissue processing for RNA isolation. RNA may get degraded if not handled and stored properly.

To counter balance this problem, proper precautions should be taken care and material should be handled and stored carefully.

• High cost of DNA & RNA purification process
• Lack of efficiency in handling of RNA samples