CUSTOM ANTIBODY SERVICE MARKET ANALYSIS

The immune system produces antibodies in response to pathogen invasion. Antigens are the collective term for the invasive bacteria, viruses, or other foreign molecules. Antibodies are proteins, or polypeptides which have specific antigen recognition sites. It is possible to have antibodies made using custom antibody production when an antibody is required against a particular antigen but it is not offered by a supplier. These antibodies can be either polyclonal or monoclonal, depending on how they are produced and harvested. Polyclonal antibodies are capable of recognizing multiple sites on an antigen. They are derived from different B-cell lineages. Monoclonal antibodies recognize only one epitope or site on an antigen, and are derived from a single B-cell line.

Global custom antibody service market is estimated to be valued at US$ 444.85 Million in 2022 and expected to reach US$ 930.46 million by 2030, witnessing a CAGR of 9.7 % over the forecast period (2022-2030).

Figure 1. Global Custom Antibody Service Market Share (%), By Region, 2022

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Market players are indulged in launching customized services for the development of custom antibodies that are used for research purposes, and this is expected to create lucrative growth opportunities in the custom antibody service market

The increase in organic strategies like new customized service launch is expected to drive the growth the market. For instance, in November 2020, AMSBIO, a leading provider of quality life science research reagents and services, announced the launch of development services for rabbit and mouse recombinant monoclonal antibodies. The DimAb development platform, a technology revolution for monoclonal antibody development, which differs from traditional hybridoma fusion methods, is the foundation for the creation of recombinant monoclonal antibodies. It can extract IgG genes from B cells of animals that have received an immunization. These antibodies aid in the creation and marketability of pharmaceuticals.

Figure 2. Global Custom Antibody Service Market Share (%) Analysis, By Product Type, 2022

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Advantages of using antibodies for various applications is projected to propel the market growth over the forecast period.

Advantages of antibodies is expected to increase their use for various applications such as research and development, production of therapeutics, etc.

According to the National Center for Biotechnology Information (NCBI): 2020, monoclonal antibodies and polyclonal antibodies are widely used in gold standard techniques such as ELISA, western blotting, flow cytometry, and other affinity based assays or isolation techniques. For ELISA, a monoclonal antibody helps detect a specific antigen of interest. Monoclonal antibodies can also help detect specific cells in flow cytometry. They are also useful for protein purification. Monoclonal antibody can further be used to bind a protein which can then be isolated from its solution.

Global Custom Antibody Service Market – Impact of Coronavirus (COVID-19) Pandemic

Since the COVID-19 outbreak in December 2019, the disease has spread to over 100 countries across the globe. The coronavirus (COVID 19) pandemic and consequent lockdown in various countries across the globe have impacted the financial status of businesses in all sectors. Supply chain and manufacturing activities have been disrupted globally, due to lockdowns implemented by governments of countries, restricted movement, and other COVID-19 safety precautions.

Identifying individuals infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a focal point throughout the coronavirus disease (COVID-19) pandemic. This has thus created a public health need for COVID-19 testing that is timely, reliable, and widely available.

Market players and academic or research institutes  are engaged in research and development activities for treatment of COVID-19 and due to this there has been increase in custom antibody services for COVID-19. This is expected to positively impact growth of the global custom antibody service market during the COVID-19 pandemic.

Global Custom Antibody Service Market: Restraint

Challenges involved in the production of customized antibodies is the major factor hampering the growth of the custom antibody services market. Some challenges includes:

• Low yield: In vitro production cultures often yield less antibody/ml than in vivo ascitic fluid method
• Cell death: Maintaining optimal cell growth and viability is essential for high antibody yields and an optimized process
• Contamination: In vitro production cultures are subject to risks of contamination associated with long-term cell cultures
• Time-consuming: In vitro production cultures often have to be maintained over a long period of time in order to yield desired quantities of antibodies