CLUSTER HEADACHE MARKET ANALYSIS

Market Concentration and Competitive Landscape

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Increasing Prevalence of Cluster Headache

Cluster headache is a severe primary headache disorder that is characterized by intense pain on one side of the head. There has been increase in cases of this disease due to greater awareness and accurate diagnosis of the condition. Earlier, cluster headache was often misdiagnosed as migraine or sinus headache due to its excruciating nature localized to one side of the head. However, with enhancement in doctors' understanding of its distinctive symptoms like periodic attacks, Horner's syndrome, and others, more patients with actual cluster headache are being identified now. Moreover, improved medical surveillance and longitudinal epidemiological research have enabled getting a clearer picture of how widespread this condition is. Several population-based studies conducted in the recent decades across countries like U.S., U.K. Canada, Italy, Norway, and others have estimated the point prevalence of cluster headache to be anywhere between 50 to 300 per 100,000 persons. The higher prevalence numbers have been reported from Norway, suggesting a possible genetic role. The disease mainly affects the adult population between 20-50 years of age with a significant male predisposition. For Instance In April 2020, according to an research article published by BMC (BioMed Central), a systematic review and meta-analysis was conducted following the guidelines of the preferred reporting items for systematic reviews and meta-analyses protocols (PRISMA-P). The study revealed that approximately 6.27% of patients with cluster headache had a family history, with an overall I2 of 73%.