CLOSTRIDIUM DIFFICILE DIAGNOSTICS AND TREATMENT MARKET ANALYSIS

Market Challenges And Opportunities

However, low awareness about clostridium difficile infection symptoms and associated effects is expected to restrain the growth of the clostridium difficile diagnostics and treatment market over the forecast period.

Robust pipeline of various therapies is expected to boost growth of the clostridium difficile treatment market over the forecast period

Standard antibiotic drugs such as metronidazole, Vancomycin, and Fidaxomicin have been used for the treatment of clostridium difficile infection (CDI) since the recent past.& Currentลy, there is no alternative therapies apart from antibiotics available for the treatment of clostridium difficile infection and only option available is surgery (in severe cases), fecal microbiota transplant, and probiotics in case of recurrent clostridium difficile infection. However, Manufacturers such as Rebiotix, Inc., Synthetic Biologics, Inc., Da Volterra, Crestovo LLC, and Immuron Ltd. have various microbiome therapeutics (new class of drugs) in pipeline for clostridium difficile infection indication. Rebiotix, Inc. has RBX7455 capsule in Phase 1 clinical trials, Synthetic Biologics Inc. has SYN-004 (ribaxamase) in Phase 2 clinical trials, and Da Volterra has DAV132 in clinical trials for antibiotic induced clostridium difficile infection. If these drugs show success in clinical trials, it could provide an alternative therapy for conventional antibiotics for treatment of the disease. Furthermore, probiotics are also gaining traction as they allow growth of natural flora through restoring natural balance of bacteria in the gut. Manufacturers such as Pfizer, Inc. and Valneva are working on developing novel vaccines for the treatment of CDI. For instance, Pfizer, Inc. has recombinant TcdA and TcdB PF-06425090 vaccine in phase 2 trial and Valneva has VLA84 in phase 1 trial.