The clomiphene citrate market is estimated to be valued at US$ 10.02 million in 2020 and is expected to exhibit a CAGR of 5.4% during the forecast period (2020-2027).
Figure 1: Clomiphene Citrate Market Share (%) Analysis, By Indication, 2020
Clomiphene Citrate Market - Impact of Coronavirus (Covid-19) Pandemic
The COVID-19 pandemic has significantly hampered demand for clomiphene citrate because the women who are under treatment of clomiphene citrate for infertility or PCOS, tests positive for COVID-19 infection, they must suspend the clomiphene citrate treatment and other fertility treatment alongside, as per the American Society for Reproductive Medicine (ASRM). However, according to the American Society for Reproductive Medicine data of March 2020, there are reports of women who have tested positive for COVID-19 delivering babies free of the COVID-19 infection. The coronavirus is not a fatal infection for a pregnant women.
The increasing rate of infertility is expected to drive growth of the clomiphene citrate market
Infertility is a health issue that affects both men and women, worldwide. Increasing infertility rates is expected to propel global demand for clomiphene citrate over the forecast period. For instance, according to the Centers for Disease Control and Prevention (CDC) report of 2018, around 6% of women aged 15 to 44 years in the U.S. were unable to conceive after one year of continuous intercourse. Furthermore, around 12% of women aged 15 to 44 years in the U.S. had difficulty in conceiving or carrying a pregnancy till child birth in 2017. Infertility also affects men. According to the same source, around 9% of men aged 25 to 44 years in the U.S. reported that they required medical help for reproduction in 2017. Clomiphene is used to treat infertility in both men and women. The U.S. FDA approved clomiphene citrate for women infertility in 1960s whereas, its often prescribed off-label for treatment of male infertility.
Figure 2: Clomiphene Citrate Market Value (US$ Mn) & Y-o-Y Growth (%), 2017-2027
Clomiphene Citrate Market – Restraints
The clomiphene citrate market is expected to be negatively affected, owing to clomiphene citrate’s inefficiency in terms of being a less effective treatment to achieve pregnancy and live child births when compared to other medicines such as Letrozole. For instance, in 2014, a team of researchers at National Institutes of Health’s (NIH) Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) found that women treated with Letrozole showed high rate of ovulation and live births than women treated with the standard drug, clomiphene citrate. Furthermore, as per the same source, among women who received Letrozole, 27.5% of them eventually had a live birth and among women who received clomiphene, only 19.1% of them experienced a live child birth. The cumulative ovulation rate was higher for Letrozole group, with ovulation occurring 61.7% of the time and the women in the clomiphene group ovulated 48.3% of the time.
Clomiphene Citrate Market Report Snapshots
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