Chronic Idiopathic Constipation (CIC) Treatment Market Dynamics
Increasing clinical trials and approval of drug candidates by pharmaceutical companies to fulfil unmet medical needs of the chronic idiopathic constipation treatment is a key factor driving the market growth over the forecast period. For instance, March 2018, Shire plc received new drug application from U.S. FDA for its drug candidate, SHP555 (prucalopride) for the indication of chronic idiopathic constipation in adults. Moreover, in 2015, SHP555 (prucalopride)received approval from European Commission for the symptomatic treatment of chronic constipation in adults with failure of laxative treatment. Furthermore, Renexxion is conducting phase 2 clinical trial for Naronapride (ATI-7505) for the treatment of multiple gastrointestinal disorders, which includes chronic idiopathic constipation. In 2017, FDA approved Ironwood and Allergan’s Linzess (linaclotide) for the treatment of chronic idiopathic constipation. However, 50% of patients with chronic constipation dissatisfied with their current treatment, mainly because of the lack of efficacy, which highlights a continued medical need for more effective and safer therapeutic agents.
However, the use of alternate therapy such as home-based remedies and herbal medication such as herbal laxative, probiotic foods etc. are expected to be major factors hindering the chronic idiopathic constipation treatment market growth.
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