CELL AND TISSUE CULTURE SUPPLIES MARKET ANALYSIS

Global cell and tissue culture supplies market is estimated to be valued at US$ 33.3 billion in 2023 and is expected to exhibit a CAGR of 12.4 % during the forecast period (2023-2030).

Analysts’ views on Global Cell and Tissue Culture Supplies Market:

Increasing prevalence of chronic diseases, new product launches, and strategies like mergers, acquisitions, and collaboration are expected drive the global cell and tissue culture supplies market growth over the forecast period. For instance, according to the data published by the World Health Organization, on February 3, 2022, cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths. Diabetes caused nearly 2.0 million while cardiovascular and respiratory diseases caused nearly 17.9 and 4.1 million deaths in 2020, respectively, worldwide. Increasing prevalence of these diseases increases the need to carry out diagnostic tests using cell culturing techniques which ultimately boosts  demand for tissue culture techniques.

Figure 1. Global Cell and Tissue Culture Supplies Market Share (%), By Product Type, 2023

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Global Cell and Tissue Culture Supplies Market – Drivers

Increasing Research and Development Activities In Tissue Culture and Cell Engineering

Increasing research and development in the field of cell and tissue engineering is expected to drive the global cell and tissue culture supplies market growth over the forecast period. For instance, on March 17, 2020, researchers from Seoul National University, South Korea, carried a study. This study proposed a method to model biomechanical-stimuli-induced blood vessel compression in vitro within a polydimethylsiloxane (PDMS) microfluidic 3D microvascular tissue culture platform with an integrated pneumatically actuated compression mechanism. 3D microvascular tissues were cultured within the device.

Increasing Launches of New Technologies and Products for Cell Culture

Increasing launch of new products to make the tissue culture process more efficient is expected to drive the global cell and tissue culture supplies market growth. For instance, on March 11, 2022, Cellink AB, a Sweden-based biotechnology company, launched the BIO CELLX platform, a novel biodispensing tool to automate 3D cell culture. It automates 3D cell culture workflows by leveraging pre-validated protocols. Bio cellx builds upon Cellink's impressive bio printing portfolio uses proven technologies like the patented clean chamber combined with a unique new method for effortless mixing of hydrogels and cells, high precision dispensing, and automatic nozzle priming to create a system for reproducible and high-throughput model generation.

Figure 2. Global Cell and Tissue Culture Supplies Market Value (US$ Million), By Region, 2023

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Global Cell and Tissue Culture Supplies Market- Regional Analysis

Among region, North America is estimated to hold a dominant position in the global cell and tissue culture supplies market over the forecast period, owing to increasing launches of products. For instance, on March 27, 2023, KromaTiD Inc., a U.S.-based biotechnology company, launched directional Genomic Hybridization (dGH) in-Site chimeric antigen receptor T-cell (CAR-T) Kit for TRAC & B2M, putting single-cell gene editing analysis technology in customer hands. The kit enables researchers to track T-cell engineering impacts on two key CAR-T cell loci, TRAC and B2M, with a level of sensitivity not achievable by using any standard FISH methods.

Global Cell and Tissue Culture Supplies Market– Impact of Coronavirus (COVID-19) Pandemic

Since the COVID-19 virus outbreak in December 2019, the disease has spread to over 100 countries across the globe, and the World Health Organization declared it a public health emergency on January 30, 2020.

COVID-19 affected the economy in three main ways: by directly affecting the production and demand of drugs, by creating disruptions in distribution channels, and through its financial impact on firms and financial markets. Due to nationwide lockdowns, several countries, such as China, India, Saudi Arabia, the U.A.E., Egypt, and others faced problems regarding transportation of drugs from one place to another.

However, the COVID-19 pandemic had positive impact on the global cell and tissue culture supplies market, due to increased demand for tissue culture products for COVID-19 testing. For instance, on January 14, 2021, Captivate Bio, a U.S.-based scientific equipment supplier, announced the launch of its portfolio of cell culture tools to assist in the fight against COVID-19 and other emerging diseases as well as to address the gaps exposed by supply chain issues and delays in cell culture media.

Global Cell and Tissue Culture Supplies Market Segmentation:

Global cell and tissue culture supplies market report is segmented into product type, application, and region.

Based on Product Type, the global cell and tissue culture supplies market is segmented into consumable products, and instruments. Out of which, consumable products segment is expected to dominate the market due to increasing launch of products.

Based on Application, the global cell and tissue culture supplies market is segmented into biopharmaceutical production, vaccine production, drug screening & development, gene therapy, toxicity testing, cancer research, and others. Among these, biopharmaceutical production segment is expected to dominate the market over the forecast period, owing to increasing research activities in biopharmaceutical companies.

Based on Region, the global cell and tissue culture supplies market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East & Africa. Among these, North America is expected to dominate the market over forecast period due to increased research and development activities.

Among all segmentation, the product type segment has the highest potential due to increasing launches of products by the key market players. For instance, on May 18, 2022, KromaTiD, a U.S.-based biotechnology company, launched PinPoint Fluorescence in Situ Hybridization (FISH) probes. The PinPoint FISH Probes build upon existing genomic assays with improved resolution and signal strength, while minimizing background noise. The probes allows rapid biomarker detection and quantification of chromosomal rearrangements, targeted mutations, and structural variants with high sensitivity. These FISH probes can be labeled as five fluorescent probe color options.

Global Cell and Tissue Culture Supplies Market Cross Sectional Analysis:

Introduction of newer products and technologies in cell culture by key market players in Europe region is expected to drive growth of instrument segment in the region. For instance, on October 12, 2022, SARSTEDT AG & Co. KG., a Germany-based medical equipment manufacturer, launched new Biofloat 96 well Ultra-Low Adherence Cell Culture plate for culturing spheroids. It not only repels cells from adhering to surface of plates but due to round bottoms of wells, cells grow in 3D spheroids. The Biofloat surface enables rapid spheroid formation within 8-24 hours with reproducibility. The chemical composition of plates allows for multiple washing steps or mechanical actions from pipetting. This plate surface is reliable.

Global Cell and Tissue Culture Supplies Market: Key Developments

On January 24, 2022, BioIVT LLC, a U.S.-based biotechnology company, launched good manufacturing practices grade human AB serum for the development and manufacturing of cell and gene therapies. Human AB serum has wide applications like it supports in vitro cell expansion by providing growth factors, vitamins, nutrients, trace elements, and transport factors found in an in vivo environment. It helps primary human cells to grow at faster rate by providing them biologically relevant conditions. This is important for autologous therapies which requires a person’s own cells or tissues. This serum is helpful for rapid development of cell cultures.

On August 10, 2021, Vita Labs Inc., a U.S.-based vitamin and dietary supplement manufacturer, collaborated with ForemostCo Inc., a U.S.-based wholesale plant nursery, to launch a tissue culture lab in Guatemala, U.S., to provide clean and healthy starting material for houseplants. This collaboration will help to strengthen the supply chain of plants. Collaboration with Vita Labs helped ForemostCo to produce high-quality, uniform planting material that can be multiplied on a year-round basis under disease-free conditions. This collaboration will help for preparing a cell culture technique that provides good quality and healthy cells.

On September 9, 2021, Cytiva Life Sciences IP Holding Corporation, a U.S.-based biopharmaceutical company, expanded its manufacturing capacity for bioprocessing single-use consumables in China, in collaboration with Wego Pharmaceutical Co. Ltd, a China-based healthcare technology supplier. The two companies expanded an existing facility jointly launched in 2018. This newly added manufacturing lines will triple the supply capacity of single-use consumables in the Asia Pacific region. In addition to the increased capacity, Cytiva Life Sciences,  launched new products, 100 Litres-1,000 Litres Xcellerex mixer bags, to the expanded facility’s manufacturing portfolio.

On August 5, 2021, Advanced Instruments LLC., a U.S.-based medical equipment manufacturer, acquired Solentim, a U.K.-based biotechnology company. Advanced Instruments’ OsmoTECH portfolio of osmometers are designed  for the biopharmaceutical industry to characterize and optimize cell culture conditions to support clonal growth and selection as well as to support upstream and downstream production processes. Solentim products are utilized in the early stages of biologic drug development to accelerate the selection of optimal clones for the production of monoclonal antibodies, gene therapies, and iPSC derived cell therapies. Advanced Instruments’ and Solentim’s technologies are synergistic, drive efficiencies, and can support improved clonal lines for use in therapeutic workflows. 

Global Cell and Tissue Culture Supplies Market: Key Trends

Introduction of newer instruments for efficient cell culturing techniques

Introduction of newer and more efficient instruments to boost up cell culturing techniques can drive growth of market. On September 28, 2022, Thermo Fisher Scientific, Inc., a U.S.-based scientific instrumentation company, launched Thermo Scientific DynaSpin Single-Use Centrifuge system. The system is designed to provide a single-use solution for large-scale cell culture harvesting. The DynaSpin system improves and streamlines harvesting for cell culture separation in single-use bioprocesses by reducing the number of depth filtration cartridges required to complete the harvest process. The DynaSpin solution provides equivalent or improved product yield compared to traditional harvest systems with higher operational efficiency, cost savings and sustainable practices in the production of biologics.

Acquisition strategy by key market players

On July 29, 2021, Sartorius AG, a Germany- based manufacturer and distributor of laboratory technology equipment, acquired Xell AG, a Germany- based biotechnology company. Through this collaboration, Sartorius AG expanded its media offering as they would be entering into specialized media production which is suitable for manufacturing of viral vectors and media analytics. Also it will help to expand the production network and get access to the analytical services of Xell for characterizing, screening, and quantifying media components, as well as optimizing media composition.

Global Cell and Tissue Culture Supplies Market: Restraints

High Cost of Cell Culture Technique

The high cost of cell and tissue culturing is expected to hamper the global cell and tissue culture supplies market growth. For instance, according to an article published by Journal of Biotechnology Advances, on April 28, 2020, the high cost associated with culturing is due to challenging scale up techniques. It is difficult to culture cell on large scale as there is high risk of contamination during cell culturing. It will contaminate the whole product.

To counterbalance this restraint, a robust protocol should be introduce to develop a tissue culture.

Lack of Infrastructure for Cell Culture

In emerging economies, lack of infrastructure facilities is expected to hamper the global cell and tissue culture supplies market growth. For instance, according to an article published in Journal Advances in Agriculture, on August 4, 2021, the major limitations faced by cell culture industry in emerging economies is inadequate funding for laboratory work, lack of infrastructure and utility services, and lack of experienced tissue culture personnel. Furthermore, an available engineer or qualified technician for maintenance and repair of tissue culture equipment are limited. The overall facility maintenance is also difficult for laboratories.

To counterbalance this restrain, more training to personnel and more funding by governments for research activities should be allocated.

Global Cell and Tissue Culture Supplies Market- Key Players

Major players operating in the global cell and tissue culture supplies market include Becton, Dickinson, and Company, Merck KGaA, Corning, Inc., Lonza Group, Eppendorf AG, Thermo Fisher Scientific, Inc., Affymetrix, Inc., GE Healthcare, VWR International, LLC, and WHEATON Industries, Inc.

Global Cell and Tissue Culture Supplies Market – Definition

Cell and tissue culture supplies are used in biotechnology, cell therapy, and regenerative medicine field. Successful plant cell/tissue culture requires high quality and dependable culture media. Various instruments that are used for cell and tissue culturing are plates, flasks, culture bags, pipetting instruments, incubators, cryostorage equipment, biosafety cabinets, and others. Increasing application of cell and tissue culture is expected to drive the global cell and tissue culture supplies market growth over the forecast period.