Cancer Vaccines MarketSize and Trends

Development of new vaccines for treatment of different cancers is expected to fuel growth of the cancer vaccines market over the forecast period

Manufacturers in the cancer vaccines market are focusing on developing new vaccines in order to treat various cancers. Through this, they are expected to gain a competitive edge in the market and increase their market share. For instance, in November 2019, NEC Corporation and VAXIMM AG, collaborated for the development of novel neoantigen cancer vaccines.

Also in July 2019, Boehringer Ingelheim International GmbH., announced the acquisition of AMAL Therapeutics SA, a company focused development of cancer immunotherapy and cancer vaccines by its KISIMA technology. The acquisition is expected to enhance Boehringer’s cancer portfolio and its cancer vaccine platform.

Gilead Science Inc., in 2017, acquired Kite Pharma Inc., which is involved in development of different type of immunotherapy and vaccines. Also, Treos Bio, in 2017, collaborated with Pharmaceutical Product Development, LLC (PPD), in order to conduct its first-in-human clinical trial for its cancer vaccine for metastatic colorectal cancer.

Furthermore, BioNTech developed RNA vaccines for mutations caused due to cancer. RNA vaccine exposes cancer cell to antigen, which is recognized by the immune system. On the other hand, Scancell’s DNA vaccine forces cancerous cell to express two antigens – gp100 and TRP-2 stimulating a strong T cell response.

In 2017, Jonsson Comprehensive Cancer Center and the Brain Tumor Center at the University of California Los Angeles (UCLA), was designated a Specialized Program of Research Excellence (SPORE) by the National Cancer Institute. The program is expected to support research into prevention, detection, and treatment of cancers and will promote co-operation among scientist in different disciplines, and also help to translate basic research from laboratories to clinical trials more quickly and effectively. Such recognition by national organizations is expected to support research in cancer vaccines.

According to a research from University of Pittsburgh School of Medicine, in 2017, a high dose flu vaccine can be used to treat people aged between 54–64 years with chronic condition such as heart disease, lung disease, diabetes, and cancer. The study is recommended for clinical trials in geriatric population.

Also, in 2017, Swiss Biotech, developed VXM01 — an attenuated bacterial vaccine modified to express vascular endothelial growth factor receptor-2 (VEGFR2), stimulates cytotoxic (killer) T cells, which will destroy cells in the vasculature feeding tumor and allow greater infiltration of immune cells. This vaccine is expected to be used for treatment in colorectal cancer and glioblastoma.

In August 2017, Imugene Limited announced the entry of its anti-cancer vaccine, HER-Vaxx for gastric cancer in 1b/2 clinical study and the phase 2 is expected to start soon.

Increasing prevalence and incidence of different cancers is expected to favor growth of the cancer vaccines market

According to WHO, in 2015, about 8.8 million people died from cancer. Moreover, tobacco related cancers was responsible for 22% deaths, lung cancer accounted for 1.69 million deaths, liver cancer led to 788,000 deaths. Colorectal, stomach, and breast cancer are estimated to cause 774,000, 754,000, and 571,000 deaths, worldwide. Increasing prevalence is a major driving factor to fuel growth of the cancer vaccines market.

According to the American Cancer Society, 2017, cancer is the second most common cause of death in the U.S., which accounts for nearly 1 out of every 4 deaths.

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