BONE GLUE MARKET ANALYSIS

Bone Glue Market Size and Trends

The Global Bone Glue Market is estimated to be valued at USD 2.91 Bn in 2024 and is expected to reach USD 4.30 Bn by 2031, exhibiting a compound annual growth rate (CAGR) of 5.7% from 2024 to 2031.

Key Takeaways of the Bone Glue Market:

• Based on type, the natural bone glue segment is expected to contribute the highest share of the market with 43.1% in 2024
• Based on application, the orthopedic surgery segment is expected to contribute the highest share of the market with 32.1% in 2024
• Based on end user, the hospitals segment is projected to contribute the highest share of the market with 43.5% in 2024
• North America is expected to top the global market with 38.3% share, followed by Asia Pacific with 26.3% share in 2024

Market Overview:

The rising geriatric population who are prone to bone-related illnesses like arthritis is prompting the increasing adoption of bone glue products for joint reconstruction and other procedures. Additionally, growing awareness about the benefits of bone glue such as lesser pain, quicker recovery time, and higher success rate of fusion is further fueling the market growth. However, the high costs associated with bone glue products and availability of alternative treatment methods may hamper the market growth to some extent during the forecast years.

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Key Developments:

• On December 11, 2024, RevBio, Inc., a clinical stage medical device company, announced the USFDA approval to expand its clinical trial for the immediate fixation of cranial flaps using TETRANITE, its bone adhesive biomaterial. The company also secured reimbursement coverage from the Centers for Medicare and Medicaid (CMS) for TETRANITE as a replacement for metal plates and screws.
• In October 2023, RevBio, Inc., a clinical stage medical device company, announced that it had been awarded a grant of up to US$ 3.4 million over three years from the National Institute on Aging (NIA), a division of the National Institutes of Health (NIH), under its Commercialization Readiness Program. The grant will support the completion of late-stage product development activities and the execution of a clinical trial to evaluate the product's safety and efficacy compared to the current standard of care.
• In December 2021, icotec ag, a manufacturer of Carbon/PEEK implants, partnered with G-21, a company specializing in medical and pharmaceutical products, to distribute G-21’s bone cements alongside icotec's VADER Pedicle Screw System in the U.S. The VADER Pedicle System is designed to restore spinal column integrity in patients with advanced-stage thoracic or lumbar spine tumors who have a limited life expectancy that precludes achieving fusion prior to oncological treatment.
• In November 2021, a study published in Frontiers in Bioengineering and Biotechnology, a multidisciplinary journal, explored the use of a biomimetic bioadhesive for gluing living bone, from initial incision to final healing. The study demonstrated that the OsStic adhesive integrates seamlessly with local bone biology in a murine bone core model, showing no signs of inflammation or adverse tissue effects.

Top Strategies Followed by Global Bone Glue Market Players

• Established Players: Leading companies in the bone glue market prioritize extensive research and development to innovate high-performance products
  • For instance, companies like Stryker and Zimmer Biomet have significantly increased their R&D budgets, focusing on developing next-generation adhesives that enhance surgical outcomes and reduce recovery times. This commitment to innovation is crucial for maintaining competitive advantage in a rapidly evolving market
• Mid-Level Players: Cost-Effective Solutions: Mid-level players focus on delivering quality, budget-friendly products targeting price-sensitive consumers
  • For instance, companies like Medtronic have introduced cost-effective bone glue options that maintain quality while appealing to hospitals looking to reduce expenses
• Small-Scale Players: Small players often target niche markets with unique features or innovative products. By focusing on specific applications or developing specialized bone adhesives, they cater to unmet needs within the broader market. The use of cutting-edge technologies, such as 3D printing and nanotechnology, enables small-scale companies to remain competitive. These technologies allow for the development of customized and high-performance bone adhesives.

Emerging Startups - Bone Glue Industry Ecosystem

• Innovative Technologies: Startups like Pixee Medical are developing advanced technologies such as augmented reality solutions for orthopedic surgery. Their innovations aim to enhance surgical precision and improve patient outcomes. The introduction of these technologies has the potential to significantly influence market dynamics by setting new standards for surgical procedures and patient care.
• Sustainable Solutions: Companies such as Anthropic are developing bone glues using sustainable biopolymers and natural compounds, while NovoBone focuses on creating bone graft substitutes from seaweed-based hydrogels. These innovative startups aim to reduce the industry's ecological footprint by offering eco-friendly alternatives to synthetic materials.