Restraints
However, stringent regulations in the U.S. such as institutions and universities that use animals for research purpose should be licensed and or registered with the U.S. department of agriculture and facilities and regulated animals must be inspected yearly by the USDA’s animal and plant health inspection service are negatively affecting the market growth due to inhibition in the production of natural glue obtained from animals.
Non-animal substitutes i.e. synthetic glue is relatively more expensive and can also lead to compatibility issues with bones. Difficulties such as irritation caused by the cement to the surrounding skin over prolong application, breakdown of the cement causes artificial joint to come loose, and breakage of cement in bits that are associated with cemented arthroplasty are main concerns.
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