BENZOCAINE MARKET ANALYSIS

Benzocaine is also known as americaine or anaesthesin and belongs to the class of organic compounds known as benzoic acid esters. Benzocaine is an active pharmaceutical ingredient having various medicinal properties. It is used as sexual disorders such as premature ejaculation, used as topical anesthetic in various diseases such as mouth and esophageal ulcers, used as pain relief drug in dental diseases such as tooth decay and dental caries, and used in relieving skin irritation such as vaginal irritation in females. Benzocaine API is manufactured in solid physical form, it is slightly soluble in water, and its chemical name is Ethyl 4-aminobenzoate.

The global benzocaine market size is estimated to be valued at US$ 128.9 million in 2020 and is expected to exhibit a CAGR of 2.70% over the forecast period (2020-2027).

Figure 1. Global Benzocaine Market Value (US$ Mn), 2016 - 2027

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Increasing prevalence of dental conditions such as dental caries, periodontal diseases, and oro-dental trauma in adults globally is a major factor driving growth of the global benzocaine market. According to World Health Organization report published in 2017, globally around 2.3 billion people suffer from dental diseases such as dental caries and pro-dental trauma causing pain and discomfort in mouth. Moreover, according to the same source, approximately 530 million children were suffering from dental diseases such as tooth decay and gum diseases globally in 2017.

Furthermore, increasing prevalence of oral ulcers, also known as recurrent aphthous ulcers, globally is another factor that is expected to drive growth of the global benzocaine market. According to US National Library of Medicine Report Published in 2018, each year, approximately 5-60% of individuals are suffering from recurrent aphthous ulcers, out of which 50% of individuals suffer from mouth irritation and pain due to ulcers.

Global Benzocaine Market – Impact of Coronavirus (Covid-19)

Following the outbreak of COVID-19 in December 2019, the disease has spread to over 100 countries across the globe and the World Health Organization has declared it a public health emergency. According to the World Health Organization’s report, the manifestation of the coronavirus (COVID-19) has resulted in more than 37 million infected individuals worldwide as of October 14, 2020.

Covid-19 has affected each and every market across the world and has also impacted the global benzocaine market in the following ways: by directly affecting the production and demand; by creating disruptions in distribution channels; and by its financial impact on firms and financial markets. Supply chain and manufacturing activities in India, China, and the U.S. have been disrupted due to nationwide lockdowns. While countries such as Saudi Arabia, UAE, Egypt, and others are facing problems with regards to transportation of drugs from one place to another.

Moreover, various guidelines are regulated by the regulating bodies during manufacturing of active pharmaceutical ingredients to avoid the spread of COVID-19 and also to reduce the contamination of active pharmaceutical ingredients during the manufacturing process. The guidelines are as follows:

According to the U.S. Food Drug and Administration Report June 2020, during the COVID-19 public health emergency, drug manufacturers should follow the following current good manufacturing practice (CGMP) regulations and recommendations regarding restriction of sick employees from production areas. Any employee or worker in production unit should be medically evaluated to check whether the individual is suffering from any infectious diseases such as COVID-19. If any of the individuals are suffering from COVID-19 symptoms, they shall be restricted from entering the production house premises in the company to avoid the contamination of drugs and active pharmaceutical ingredients (API).

Figure 2. Global Benzocaine Market Share (%), by Region, 2020

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Among regions, North America is expected to witness significant growth in the benzocaine market during the forecast period, owing to key companies focusing on benzocaine API product launches and product approvals for treatment of various diseases such as vaginal irritation due to urinary tract infections. For instance, in 2019, Church and Dwight, Co. launched RepHresh Cooling Relief spray with active ingredient benzocaine for the treatment and relief from vaginal irritation caused in females due to urinary tract infections. RepHresh Cooling Relief Vaginal Anti-Itch Spray will be supplied as 15mL tubes providing up to 60 uses throughout in the U.S.

Key Players

Major players operating in the global benzocaine market include TCI Chemicals (India) Pvt. Ltd, Merck KGaA, ACETO Corporation, Alfa Aesar, Penta International Corporation, abcr GmbH, Indofine Chemical Co Inc, Jinzhou Jiutai Pharmaceutical Co., Ltd, Changzhou Sunlight Pharmaceutical Raw Material Co., Ltd, Fengchen Group Co., Ltd, and Mahendra Chemicals.