Global Anti-malarial Drugs Market: Key Developments
In December 2022, MMV, a product development partnership in the field of antimalarial drug research and development, and the Africa Centers for Disease Control and Prevention (Africa CDC), a public health agency of the African Union to support the public health have signed a Memorandum of Understanding (MoU), focused on strengthening African manufacturing of malaria medicines on the margins of the 2nd International Conference on Public Health in Africa (CPHIA 2022), taking place in Kigali, Rwanda.
In August 2022, the World Health Organization has approved Kenyan producer Universal Corporation Ltd (UCL) to support regional efforts to eradicate malaria by producing high-quality sulfadoxine-pyrimethamine locally (SP). Such initiatives will lead to rise in local production of anti-malarial therapies.
In October 2022, Lumen Bioscience, Inc., a clinical-stage biotechnology company developing topically and mucosally delivered biologic drugs to treat and prevent highly prevalent diseases, announced the publication of data demonstrating a needle-free, spirulina-produced recombinant vaccine that protects against malaria. The research, conducted in collaboration with the University of Washington, was published in the peer-reviewed journal, Nature Partner Journals (NPJ) Vaccines. Lumen Bioscience pioneered genetic engineering methods to highly express bioactive proteins in spirulina. The published research details how this platform was used to express a malaria protein antigen that can be delivered intranasally and later boosted with a simple oral booster. Treated mice demonstrated protection against subsequent malaria challenge. The low cost and scalability of Lumen's production platform, coupled with easy, needle-free administration, could greatly expand real-world access to malaria vaccines.
On May 2, 2023, Southwest Research Institute (SwRI), an independent and nonprofit applied research and development organization and The University of Texas at San Antonio (UTSA), a public research university have developed a method to synthesize the highly potent antimalarial drug artemisinin, which could lead to a more cost-effective treatment for malaria. The work, recently featured on the cover of the scientific journal Organic Letters, was supported by the Bill and Melinda Gates Foundation as well as a grant from the Connecting through Research Partnerships (Connect) program, a joint effort by SwRI and UTSA to enhance scientific collaboration between the two institutions.
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