ALZHEIMERS DRUGS MARKET ANALYSIS

Market Concentration and Competitive Landscape

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Novel Drug Targets and Pipeline Progress

After multiple past failures in treatment development for Alzheimer's, the currently approved medicines can only manage symptoms temporarily without altering disease progression. There has been promising pipeline activity that explores novel mechanisms and molecular targets beyond the amyloid hypothesis. Several companies are developing disease-modifying drugs targeting tau tangles, neuroinflammation, synaptic dysfunction, and other pathways increasingly implicated in Alzheimer's pathology. Large late-stage trials are ongoing to evaluate anti-amyloid antibodies as well as anti-tau antibodies and small molecules for preventing or slowing cognitive decline. Some potential first-in-class therapies for early Alzheimer's include anti-Tau antibody crenezumab from Genentech and anti-amyloid gamma secretase modulator verubecestat from Merck.