ACUTE HEART FAILURE (AHF) THERAPEUTICS MARKET ANALYSIS

Acute Heart Failure (AHF) Therapeutics MarketSize and Trends

Acute Heart Failure (AHF) Therapeutics Market Drivers

The global acute heart failure therapeutics market is expected to witness significant growth due to approval of new drugs. For instance, in July 2015, Novartis received U.S. Food and Drug Administration (FDA) approval for their Entresto(TM) (sacubitril/valsartan) tablets on the treatment of heart failure with reduced ejection fraction. Entresto is indicated to reduce the risk of cardiovascular death and heart failure hospitalization.

Furthermore, robust pipeline of drugs over the forecast period (2018-2026), is another factor driving growth of acute heart failure therapeutics market. For instance, in March 2017, Cardioxyl Pharmaceuticals’ CXL-1427: a novel nitroxyl (HNO) donor (prodrug), which now operates under the Bristol-Myers Squibb Company (after Cardioxyl Pharmaceuticals’ acquisition by Bristol-Myers Squibb in December 2015); is present in Phase 2 clinical development phase. CXL-1427 is indicated to use as an intravenous treatment for acute decompensated heart failure (ADHF). Successful completion and further launch of Bristol-Myers Squibb’s innovative drug in future, will help to boost the acute heart failure (AHF) therapeutics market growth during the forecast period.

Market- Trends

Various lifestyle factors are responsible to increase risk heart attack and stroke, which includes smoking, overweight, eating foods with high fat and cholesterol, and physical inactivity. Furthermore, patients suffering with heart failure are at high risk to one or more conditions such as coronary artery disease, myocardial infraction, high blood pressure or hypertension, abnormal heart valves, dilated cardiomyopathy, hypertrophic cardiomyopathy, severe lung disease, obesity, and sleep apnea, among others. For instance, according to the World Health Organization (WHO), October 2017 data findings, in 2016, over 1.9 billion adults, were overweight, worldwide. Among which over 650 million were obese. Moreover, according to the same source, raised BMI index, owing to overweight and obesity are the major risk factors for cardiovascular disease, which was the leading cause of death in 2012, worldwide.