DNA nanotechnology is an emerging field that utilizes the unique properties of DNA to engineer novel arrangements of DNA, and manipulate materials at the nanoscale level. By exploiting the highly specific binding properties of DNA base pairs, DNA nanotechnology allows scientists to construct dynamic devices and structures from DNA and other materials. DNA nanotechnology holds significant promise for applications across various industries, including healthcare, electronics, and materials. It enables the development of programmable and addressable nanoscale structures, devices, and systems through the molecular recognition and self-assembly capabilities of DNA and other nucleic acids. Advances in DNA origami techniques now allow researchers to fold long single strands of DNA into predefined two-dimensional and three-dimensional shapes at the nanoscale. Continued progress in DNA nanotechnology is poised to revolutionize fields such as drug delivery, synthetic biology, nanoelectronics, and more.
Market Dynamics:
Drivers such as the growing focus on nanotechnology-based diagnostic techniques, rising investments in the development of targeted drug delivery methods, and increasing adoption of DNA nanotechnology for various applications are fueling the growth of the DNA nanotechnology market. However, high costs associated with DNA nanotechnology research and technical limitations related to DNA origami fabrication are expected to restrain the market growth. Meanwhile, emerging opportunities lie in the application of DNA nanotechnology in material science for developing functional materials with unique properties. Advances in automated DNA origami design, modeling, and fabrication also hold promise to help address existing challenges and further stimulate market growth in the coming years.
DNA nanotechnology utilizes the molecular recognition properties of DNA and other nucleic acids to create complex, programmable structures at the nanoscale. DNA nanotechnology can be used to develop highly sensitive biosensors for the detection of biomarkers associated with various diseases, improving diagnostic capabilities. DNA nanostructures can be designed to carry and release drug molecules in a controlled manner, targeting specific cells or tissues, which has implications for cancer therapy, among other diseases. DNA-based nanostructures can serve as precise imaging agents, enhancing the resolution and specificity of imaging techniques. Beyond drug delivery, DNA nanotechnology may enable gene regulation therapies and the construction of nano-scale devices that can interact with biological systems for therapeutic purposes. DNA has the potential to revolutionize computing by providing a medium for high-density data storage and the development of biological computing systems. DNA nanotechnology is being used to create novel materials with programmable functions and properties, impacting industries from electronics to biotechnology
For instance, in September 2023, RNA Institute in the College of Arts and Sciences, a research institute, received US$1.9 million from the National Institute of General Medical Sciences, a branch of the National Institutes of Health, to support research exploring ways to exploit DNA nanotechnology for biomedical and materials science applications.
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