Global Barrett’s esophagus market is estimated to be valued at USD 5.05 Bn in 2024 and is expected to reach USD 7.20 Bn by 2031, growing at a compound annual growth rate (CAGR) of 5.2% from 2024 to 2031.
Barrett's esophagus is a condition where the lining of the esophagus is damaged due to chronic acid reflux. It is a serious complication of gastroesophageal reflux disease (GERD) where the lining of the esophagus is replaced by the abnormal tissue similar to the lining of the intestine. This change in the cells of the esophagus can increase the chances of developing esophageal adenocarcinoma, a type of esophageal cancer. Barrett's esophagus usually does not cause symptoms but can be diagnosed by esophagogastroduodenoscopy (EGD) along with biopsy. The key predisposing factor is chronic GERD where stomach acid damages the esophagus over many years. Other risk factors include obesity, smoking, and male gender. The condition needs to be closely monitored as it is a precursor to esophageal cancer. Treatment involves lifestyle modifications and medication to control acid reflux. In some cases, radiofrequency ablation or endoscopic mucosal resection may be recommended to remove dysplastic tissues.
Market Dynamics:
Global Barrett’s esophagus market growth is driven by increasing prevalence of gastroesophageal reflux disease (GERD) and obesity rates worldwide. Chronic and untreated GERD are major risk factors for Barrett’s esophagus. According to the National Institute of Diabetes and Digestive and Kidney Diseases Report published in 2020, approximately 60 million Americans experience heartburn at least once a month. Obesity is another important factor predisposing to GERD due to excess pressure on the abdomen. The market also stands to benefit from routine screening practices for esophageal cancer. However, the market growth can be restrained by the asymptomatic nature of Barrett’s esophagus leading to underdiagnoses in some cases. Lack of approved drugs for the treatment and high cost of management procedures also challenges the market to some extent. Nevertheless, ongoing research on novel diagnostic biomarkers and therapeutic strategies present lucrative opportunities in the long run.
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