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GLOBAL AUTOIMMUNE POLYGLANDULAR SYNDROME TYPE 1 MARKET SIZE AND SHARE ANALYSIS - GROWTH TRENDS AND FORECASTS (2023 - 2030)

Global Autoimmune Polyglandular Syndrome Type 1 Market, By Diagnosis (Serum Autoimmune Screen, End-organ Function Tests, Blood Tests), By Treatment (Medication, Antifungal Agents, Fluconazole, Itraconazole, Calcitriol, Corticosteroids, Others), By Dosage Form (Tablet, Capsule, Others), By Route of Administration (Oral, Others), By Age of Onset (Childhood, Adult, Adolescent), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies), By Geography (North America, Europe, Asia Pacific, Latin America, Middle East and Africa)

  • Published In : Jan 2024
  • Code : CMI6538
  • Pages :172
  • Formats :
      Excel and PDF
  • Industry : Pharmaceutical
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Autoimmune polyglandular syndrome type 1 (APS1), also known as autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), is a rare multisystem disorder caused by the autoimmune destruction of several endocrine glands like the adrenals, parathyroid glands, gonads, and other tissues. APS1 results from mutations in the AIRE gene (autoimmune regulator), which regulates the expression of tissue-specific genes and promotes central tolerance induction. Loss of function of AIRE leads to failures in immune tolerance, leading to autoimmune attacks on multiple organs. Common clinical features of APS1 include hypoparathyroidism, primary adrenal insufficiency, chronic mucocutaneous candidiasis, and gonadal failure. Early onset and severity of multiorgan involvement require lifelong management and monitoring of APS1 patients.

Market Dynamics:

The global autoimmune polyglandular syndrome type 1 market is projected to witness lucrative growth opportunities owing to rising APS1 disease prevalence worldwide. Genetic screening programs for high-risk ethnic populations are driving the early diagnosis rate. Increasing research into understanding immunological disease mechanisms and developing novel tolerance-inducing therapies is also fueling market growth. However, a lack of approved targeted drugs and limited treatment options continue to hamper the market. Meanwhile, initiatives to enhance rare disease awareness and focus on developing new biologics hold potential to create attractive opportunities. As a rare disease, APS-1 may benefit from orphan drug designations and incentives to encourage research and development. Ongoing research aims to deepen our understanding of the underlying mechanisms, allowing for more targeted and effective treatments. However, the limited patient population poses challenges for large-scale clinical trials and drug development.

Collaboration between pharmaceutical companies, research institutions, and patient advocacy groups is crucial for advancing APS-1 research and improving the quality of life for individuals affected by this complex autoimmune syndrome. The market dynamics are influenced by both medical advancements and the regulatory landscape supporting rare disease treatments.

Key features of the study:

- This report provides in-depth analysis of the global autoimmune polyglandular syndrome type 1 market, and provides market size (US$ Million) and compound annual growth rate (CAGR%) for the forecast period (2023–2030), considering 2022 as the base year

- It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market

- This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players

- It profiles key players in the global autoimmune polyglandular syndrome type 1 market based on the following parameters – company highlights, products portfolio, key highlights, financial performance, and strategies

- Key companies covered as a part of this study include Pfizer Inc., GlaxoSmithKline plc, Novartis AG, Mylan N.V., Teva Pharmaceutical Industries Ltd., Sanofi, F. Hoffmann-La Roche Ltd., Zydus Cadila, Lupin, Amneal Pharmaceuticals LLC., Cipla Inc., Aurobindo Pharma, Glenmark Pharmaceuticals Limited, Eli Lilly and Company, Sun Pharmaceutical Industries Ltd., Allergan, Bristol-Myers Squibb Company, Takeda Pharmaceutical Company Limited, Abbott, and LEO Pharma A/S.

- Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics

- The global autoimmune polyglandular syndrome type 1 market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts

- Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global autoimmune polyglandular syndrome type 1 market

Detailed Segmentation:

  • By Diagnosis
    • Serum Autoimmune Screen
    • End-organ Function Tests
    • Blood Tests
  • By Treatment
    • Medication
    • Antifungal Agents
    • Fluconazole
    • Itraconazole
    • Calcitriol
    • Corticosteroids
    • Others (Hormone Replacement Therapy, etc.)
  • By Dosage Form
    • Tablet
    • Capsule
    • Others
  • By Route of Administration
    • Oral
    • Others
  • By Age of Onset
    • Childhood
    • Adult
    • Adolescent
  • By Distribution Channel
    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies
  • By Region
    • North America
    • Europe
    • Asia Pacific
    • Latin America
    • Middle East
    • Africa
  • Key Players:
    • Pfizer Inc.
    • GlaxoSmithKline plc
    • Novartis AG
    • Mylan N.V.
    • Teva Pharmaceutical Industries Ltd.
    • Sanofi
    • F.Hoffmann-La Roche Ltd.
    • Zydus Cadila
    • Lupin
    • Amneal Pharmaceuticals LLC.
    • Cipla Inc.
    • Aurobindo Pharma
    • Glenmark Pharmaceuticals Limited
    • Eli Lilly and Company
    • Sun Pharmaceutical Industries Ltd.
    • Allergan
    • Bristol-Myers Squibb Company
    • Takeda Pharmaceutical Company Limited
    • Abbott
    • LEO Pharma A/S

Detailed Segmentation:

  • By Diagnosis
    • Serum Autoimmune Screen
    • End-organ Function Tests
    • Blood Tests
  • By Treatment
    • Medication
    • Antifungal Agents
    • Fluconazole
    • Itraconazole
    • Calcitriol
    • Corticosteroids
    • Others (Hormone Replacement Therapy, etc.)
  • By Dosage Form
    • Tablet
    • Capsule
    • Others
  • By Route of Administration
    • Oral
    • Others
  • By Age of Onset
    • Childhood
    • Adult
    • Adolescent
  • By Distribution Channel
    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies
  • By Region
    • North America
    • Europe
    • Asia Pacific
    • Latin America
    • Middle East
    • Africa
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