Azelaic acid is a naturally occurring dicarboxylic acid that is found in grains such as barley and wheat. It is used topically in the treatment of mild to moderate acne as it has antibacterial and anti-inflammatory properties. Azelaic acid reduces non-inflammatory lesions such as whiteheads, blackheads, and papules, along with reducing inflamed such as pustules and nodules. When applied to the affected skin, azelaic acid targets the bacteria Propionibacterium acnes, which resides within hair follicles and sebaceous glands. Additionally, it helps lighten areas of hyperpigmentation caused by acne by inhibiting tyrosinase, an enzyme involved in melanin production. Due to its antimicrobial effects, mild nature, and minimal side effects, azelaic acid has become an important topical treatment option for acne.
Market Dynamics:
The global azelaic acid market is driven by the increasing prevalence of acne vulgaris worldwide, particularly among young adults and adolescents. According to the American Academy of Dermatology, acne affects up to 50 million Americans annually, accounting for over 13 billion dollars in costs every year. Azelaic acid is a safe and effective treatment option for mild to moderate acne, making it appealing for use by teenagers. Additionally, its properties of skin lightening and fading post-inflammatory hyperpigmentation have led to an increased demand of azelaic acid in cosmetic products. However, alternatives available in the market including prescription isotretinoin and antibiotics, pose a threat to the azelaic acid market share. Furthermore, the generally higher cost of these pharmaceutical grade azelaic acid products as compared to other acne medications can hamper market growth. Nonetheless, the development of innovative drug delivery systems and combined high concentration gels and creams provides new opportunities for industry players in this space.
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