Table of Content - Downstream Processing Market

Downstream processing refers to the purification and recovery steps in bioprocessing undertaken after fermentation to isolate the active ingredient or product of interest from cellular biomass or fermentation broth. It involves clarification to remove cellular debris and components, concentration to separate and recover the target product by reducing volume, and final purification using chromatographic techniques. Downstream processing plays a critical role in ensuring the purity, quality, and stability of biopharmaceutical products, thereby determining their success in the market. Advances in technologies for clarification and purification such as expanded bed chromatographic separation and continuous processing have enabled higher product yields and throughput at reduced costs of goods.

Market Dynamics:

The downstream processing market growth is driven by the rapid growth of the biopharmaceutical industry, preference for biologics over small molecule drugs, and strong demand for monoclonal antibodies and vaccines. However, high costs associated with downstream purification equipment and operations acts as a restraint. Advancements in continuous manufacturing and single-use technologies provide significant opportunities for market players to develop innovative solutions for integrated and modular processes. Market leaders are focusing on partnerships and M&A activities to strengthen their portfolio of purification solutions and chromatography resins.

Key features of the study:

This report provides in-depth analysis of the global downstream processing market, and provides market size (USD Million) and compound annual growth rate (CAGR%) for the forecast period (2024–2031), considering 2023 as the base year
It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
It profiles key players in the global downstream processing market based on the following parameters – company highlights, products portfolio, key highlights, financial performance, and strategies
Key companies covered as a part of this study include GE Healthcare, Merck KGaA, Thermo Fisher Scientific Inc., 3M Company, Lonza Group AG, Eppendorf AG
Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
The global downstream processing market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global downstream processing market

Detailed Segmentation-

By Technique
- Purification Techniques
- Solid-Liquid Separation
- Clarification/Concentration
By Product
- Chromatography Columns and Resins
- Filters
- Evaporators
- Centrifuges
- Other Products
By Application
- Antibodies Production
- Vaccines Production
- Insulin Production
- Other Application
By End User
- Biopharmaceutical Companies
- CMOs/CDMOs
- Research Institutes
- CROs
- Others
By Region:
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East
- Africa
Company Profiles:
- Merck KGaA
- Thermo Fisher Scientific Inc.
- GE Healthcare
- Sartorius Stedim Biotech S.A.
- Repligen Corporation
- Pall Corporation
- M Company
- Eppendorf AG
- Agilent Technologies, Inc.
- Waters Corporation
- Shimadzu Corporation
- Bio-Rad Laboratories, Inc.
- Avantor Performance Materials, LLC
- Tosoh Corporation
- Column Technology Inc.
- Purolite
- R. Grace & Co.
- Asahi Kasei Corporation
- Novasep Holding S.A.S
- Boehringer Ingelheim

Table of Contents

Research Objectives and Assumptions
- Research Objectives
- Assumptions
- Abbreviations
Market Purview
- Report Description
  - Market Definition and Scope
- Executive Summary
  - Market Snapshot, By Technique
  - Market Snapshot, By Product
  - Market Snapshot, By Application
  - Market Snapshot, By End User
  - Market Snapshot, By Region
- Coherent Opportunity Map (COM)
Market Dynamics, Regulations, and Trends Analysis
- Market Dynamics
  - Drivers
  - Restraints
  - Opportunities
- Impact Analysis
- Market Trends
- Key Developments
- Regulatory Scenario
- Acquisitions and Partnerships Scenario
- Funding and Investments
- PEST Analysis
- Porter’s Analysis
Global Downstream Processing Market - Impact of Coronavirus (COVID-19) Pandemic
- Overall Impact
- Government Initiatives
- COVID-19 Impact on the Market
Global Downstream Processing Market, By Technique, 2019 – 2031, (USD Mn)
- Overview
  - Market Share Analysis, 2024 and 2031 (%)
  - Y-o-Y Growth Analysis, 2020 – 2031
  - Segment Trends
- Purification Techniques
  - Overview
  - Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Mn)
- Solid-Liquid Separation
  - Overview
  - Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Mn)
- Clarification/Concentration
  - Overview
  - Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Mn)
Global Downstream Processing Market, By Product, 2019 – 2031, (USD Mn)
- Overview
  - Market Share Analysis, 2024 and 2031 (%)
  - Y-o-Y Growth Analysis, 2020 – 2031
  - Segment Trends
- Chromatography Columns and Resins
  - Overview
  - Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Mn)
- Filters
  - Overview
  - Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Mn)
- Evaporators
  - Overview
  - Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Mn)
- Centrifuges
  - Overview
  - Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Mn)
- Others
  - Overview
  - Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Mn)
Global Downstream Processing Market, By Application, 2019 – 2031, (USD Mn)
- Overview
  - Market Share Analysis, 2024 and 2031 (%)
  - Y-o-Y Growth Analysis, 2020 – 2031
  - Segment Trends
- Antibodies Production
  - Overview
  - Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Mn)
- Vaccines Production
  - Overview
  - Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Mn)
- Insulin Production
  - Overview
  - Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Mn)
- Other Applications
  - Overview
  - Market Size and Forecast, and Y-o-Y Growth, 2019–2031, (USD Mn)
Global Downstream Processing Market, By Region, 2019 – 2031, (USD Mn)
- Introduction
  - Market Share Analysis, By Region, 2024 and 2031 (%)
  - Y-o-Y Growth Analysis, For Region, 2020–2031
  - Regional Trends
- North America
  - Introduction
  - Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 – 2031, (USD Mn)
    - U.S.
    - Canada
- Latin America
  - Introduction
  - Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 – 2031, (USD Mn)
    - Brazil
    - Mexico
    - Argentina
    - Rest of Latin America
- Europe
  - Introduction
  - Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 – 2031, (USD Mn)
    - U.K.
    - Germany
    - Italy
    - France
    - Spain
    - Russia
    - Rest of Europe
- Asia Pacific
  - Introduction
  - Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 – 2031, (USD Mn)
    - China
    - India
    - Japan
    - ASEAN
    - Australia
    - South Korea
    - Rest of Asia Pacific
- Middle East
  - Introduction
  - Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 – 2031, (USD Mn)
    - GCC
    - Israel
    - Rest of Middle East
- Africa
  - Introduction
  - Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Mn)
  - Market Size and Forecast, and Y-o-Y Growth, By Country/Region, 2019 – 2031, (USD Mn)
    - North Africa
    - Central Africa
    - South Africa
Competitive Landscape
- Company Profiles
  - Merck KGaA
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Thermo Fisher Scientific Inc.
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - GE Healthcare
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Sartorius Stedim Biotech S.A.
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Repligen Corporation
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Pall Corporation
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - M Company
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Eppendorf AG
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Agilent Technologies, Inc.
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Waters Corporation
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Shimadzu Corporation
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Bio-Rad Laboratories, Inc.
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Avantor Performance Materials, LLC
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Tosoh Corporation
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Column Technology Inc.
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Purolite
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - W.R. Grace & Co.
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Asahi Kasei Corporation
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Novasep Holding S.A.S
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
  - Boehringer Ingelheim
    - Company Highlights
    - Product Portfolio
    - Key Highlights
    - Financial Performance
    - Market Strategies
Analyst Recommendations
- Wheel of Fortune
- Analyst View
- Coherent Opportunity Map
References and Research Methodology
- References
- Research Methodology
- About us and Sales Contact

*Browse 32 market data tables and 28 figures on "Downstream Processing Market” - Global forecast to 2031

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