Global leuprolide acetate market is estimated to be valued at USD 3.82 Billion in 2024 and is expected to reach USD 5.81 Billion by 2031, exhibiting a compound annual growth rate (CAGR) of 6.2% from 2024 to 2031.
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Global leuprolide acetate market growth is driven by factors such as increasing incidence of prostate cancer and endometriosis across the globe. According to the National Cancer Institute, prostate cancer is one of the most common cancers affecting men worldwide. Leuprolide acetate is widely used for treating prostate cancer and endometriosis-related pain. Moreover, development of advanced drug delivery formulations of leuprolide acetate providing enhanced efficacy and reduced treatment duration can also drive the market growth during the forecast period.
Increasing prevalence of prostate cancer
Rising prevalence of prostate cancer can drive the global leuprolide acetate market growth. Prostate cancer has been occurring at an alarming rate due to factors like genetics, diet, lifestyle and environmental factors. As per estimates by medical experts, 1 in every 8 men is likely to be diagnosed with prostate cancer in their lifetime. Aging global population has also meant that the at-risk population base is rapidly rising. Leuprolide acetate is one of the leading drugs used in the treatment of prostate cancer. It is a gonadotropin-releasing hormone (GnRH) agonist drug that works by stopping the production of testosterone by the testes, thus, slowing or stopping the growth of prostate cancer tumors that need testosterone to grow.
As testosterone production decreases or stops with leuprolide acetate treatment, the prostate tumor size usually decreases significantly or disappears in patients responding to therapy. It is commonly used as a go-to treatment for cancer that has spread to other parts of the body or for cancer that does not respond to initial hormone treatment or radiation therapy. Rising incidence rates and growing acceptance of leuprolide acetate as a preferred treatment option can boost demand from urologists and oncologists.
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Rising demand for effective drugs in breast cancer treatment
Rising prevalence of breast cancer cases globally has boosted demand for advanced treatment options and effective pharmaceutical products. Breast cancer is one of the leading causes of cancer-related deaths among women. While awareness and screening programs have helped in early detection, a sizeable number still present with advanced or metastatic stages of the disease. Leuprolide acetate plays a vital role as an effective treatment alternative, especially for estrogen receptor positive breast cancer.
As a powerful GnRH agonist, Leuprolide acetate works to indirectly deprive cancer cells of estrogen through suppression of ovarian function. This helps stop or slow the growth and spread of hormone-dependent breast tumors. It is commonly used for pre-menopausal women with advanced breast cancer, either alone or together with other drugs like aromatase inhibitors. By inducing a drug-induced menopause, it deprives the cancer cells of the hormonal stimulation these need to grow. With proven efficacy and fewer side effects than surgical removal of ovaries, it has become a core treatment component for thousands of patients annually. Moreover, growing focus on quality of life has boosted usage of leuprolide acetate as it maintains pregnancy ability after completion of therapy. Rising prevalence of breast cancer cases, combined with increasing adoption of leuprolide acetate as a therapy option, can drive the market growth.
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