The incretin mimetics market faces several challenges in further growth. As newer treatment options emerge for type 2 diabetes, some incretin mimetics face increasing competition. The delivery methods of some drugs have faced patient adherence challenges. Further, the patent expirations of major brands in the next 2-3 years could enable the entry of cheaper generics, exerting downward pressure on prices.
Market Opportunities: Research and Development Activities
Research and development activities in the area of incretin mimetics present a significant opportunity for growth in this market. Incretin mimetics are a class of drugs that mimic the effects of natural incretins like GLP-1 and GIP. These important gastrointestinal hormones play a key role in regulating important processes like glucose-dependent insulin secretion, suppression of glucagon secretion, delay in gastric emptying, etc.
By focusing more resources on research and development, pharmaceutical companies can develop more advanced incretin mimetic drugs with improved efficacy, safety, and novel delivery mechanisms. Currently available drugs in this class, like exenatide and liraglutide have revolutionized diabetes treatment. However, long term adherence can be challenging due to factors like frequent injections. R&D can help address these limitations by coming up with newer oral or non-injectable formulations of incretin mimetics. Several companies already have novel drug candidates in the late stages of clinical trials that offer weekly or monthly dosing options instead of daily injections.
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