Graves Disease Overactive Thyroid Market Size and Trends

Global graves' disease (overactive thyroid) market is estimated to be valued at USD 410.1 Mn in 2024 and is expected to reach USD 570.2 Mn by 2031, exhibiting a compound annual growth rate (CAGR) of 4.8% from 2024 to 2031.

Graves’ Disease (Overactive Thyroid) Market Key Factors

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Graves' disease, an autoimmune disorder causing hyperthyroidism, is one of the leading causes of too much thyroid hormone in the blood. Graves' disease (overactive thyroid) market is expected to witness steady growth due to rising incidence rates of graves' disease worldwide. Increasing adoption of innovative therapies and pipeline drugs for improved treatment outcomes of graves' disease can also drive the market growth. However, social consequences of the pandemic and economic uncertainties can negatively impact the market growth. Increased awareness and improved diagnosis of this disease can drive the market growth over the forecast period. For instance, in April 2020, according to the article published on 'What is the Prevalence of Graves' Disease in the US?', Graves' disease stands as the leading cause of hyperthyroidism in the U.S., with an estimated incidence rate of about 30 cases per 100,000 individuals annually. This high prevalence places a significant burden on healthcare systems, thus, boosting demand for therapeutic and diagnostic solutions.

Risk Factors Contributing to Graves' Disease Prevalence

Rising prevalence of Graves' disease can be attributed to various lifestyle and genetic risk factors that make individuals more susceptible to developing the condition. Studies have shown that Graves' disease is more common in women, with the female to male ratio being approximately 7.5:1. Fluctuating estrogen levels during periods of reproductive life like puberty, pregnancy and menopause can influence the autoimmune process. As more women are delaying childbearing and pregnancy to later ages due to social and career reasons, it increases their exposure to these hormonal changes. Family history of other autoimmune diseases like thyroiditis, vitiligo and diabetes also increases the risk of the disease. Environmental pollutants like cigarettes, air pollutants and high nitrate levels in food and water have been implicated in disturbing the autoimmune balance in genetically predisposed individuals. Increasingly fast-paced lifestyle with prolonged periods of mental and physical stress weakens the body's natural defense mechanisms. Moreover, modern industrial food production relies heavily on excessive use of fertilizers and preservatives which leads to higher consumption of these risk factors via various food sources on a daily basis. All of these lifestyle and genetic determinants aggregately contribute to rising incidence of Graves' disease.

Growing Awareness Propelling Earlier Diagnosis

Increased global focus on thyroid health in recent years has boosted awareness and detection rates for Graves' disease. Nowadays, people are more knowledgeable about symptoms of an overactive thyroid like unintended weight loss, palpitations, eye bulging, and others, thus, these people seek medical advice for evaluation. Moreover, diagnostic advancements have made it possible for doctors to identify thyroid abnormalities much earlier through sensitive blood tests and thyroid scans. This results in more Graves' disease cases being picked up at mild and moderate stages rather than at later severe phases. Growing number of specialized endocrinology centers and availability of expert doctors in both rural and urban areas have further strengthened healthcare access and diagnostic infrastructure. Population-wide screening programs for early thyroid issues have also been launched in several countries. Integrated with hyperlocal health outreach initiatives, these measures enables timely diagnosis of Graves' disease in communities.