Global Barrett’s esophagus market is estimated to be valued at USD 5.05 Bn in 2024 and is expected to reach USD 7.20 Bn by 2031, growing at a compound annual growth rate (CAGR) of 5.2% from 2024 to 2031.
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The market is expected to witness positive growth over the forecast period due to rising geriatric population worldwide who are more prone to gastroesophageal reflux disease (GERD) and subsequent development of Barrett’s esophagus. Additional factors such as increasing obesity rates, growing adoption of unhealthy lifestyles and rising smoking prevalence are also expected to drive the risk of GERD, and fuel the market growth. However, lack of symptoms in early stages of Barrett’s esophagus may limit the market size potential to a certain extent.
Rising Prevalence of Gastroesophageal Reflux Disease
One of the key drivers for growth of the global Barrett's esophagus market is increasing prevalence of gastroesophageal reflux disease (GERD) across global populations. GERD is a common condition that affects the digestive system, and causes a burning sensation in the chest or throat known as acid reflux. Long term or frequent reflux increases the risk of damage to the esophageal lining over time and may result in Barrett's esophagus.
Various lifestyle and dietary habits have contributed to higher instances of obesity and poor digestion. Consumption of fatty, spicy or acidic foods combined with lifestyle stress can weaken the lower esophageal sphincter, causing stomach acids to back up. This has led to a surge in GERD cases in recent decades. Changing demographics with aging populations also play a role as elderly individuals are more vulnerable to this condition. According to BMC Public Health Journal in 2023, globally, the prevalence of GERD grew significantly from 441.6 million to 783.9 million between 1990 and 2019, whereas the age-standardized prevalence rate increased little from 9,344.52 per 100,000 in 1990 to 9,574.45 per 100,000 in 2019.
Growing prevalence of GERD is a driver for Barrett's esophagus as prolonged reflux exposes the esophagus to damaging stomach acids over many years. This increases the chances of cellular changes developing in the esophagus lining. As lifestyle-related risk factors continue and populations age further, it is expected that the number of GERD patients will keep growing which will directly influence growth of Barrett's esophagus as well.
Another major factor augmenting growth of global Barrett's esophagus market is greater efforts towards screening and diagnosis combined with raising awareness. Barrett's esophagus itself does not produce noticeable symptoms in early stages. As a result, many cases remain undiagnosed for long periods until complications appear. However, medical experts now recognize timely screening of high-risk groups as crucial for catching pre-cancerous changes early and improving treatment outcomes.
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