DIABETIC KIDNEY DISEASE MARKET SIZE AND SHARE ANALYSIS - GROWTH TRENDS AND FORECASTS (2024-2031)

Diabetic Kidney Disease Market Size and Trends

Global diabetic kidney disease market is estimated to be valued at USD 3.03 Bn in 2024 and is expected to reach USD 4.21 Bn by 2031, exhibiting a compound annual growth rate (CAGR) of 4.8% from 2024 to 2031.

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Increasing prevalence of diabetes across the globe is primarily driving the market growth. According to the International Diabetes Federation 2021 Report, approximately 537 million people lived with diabetes in 2021 worldwide and this number is expected to rise to 643 million by 2030 and 783 million by 2045. The market is witnessing significant growth due to rising awareness regarding diabetic kidney disease and availability of various treatment options. Furthermore, developments in areas such as diagnostic tools, drugs, and renal replacement therapies are helping patients in early detection and effective management of the disease. However, high cost of treatment devices and lack of awareness in low-income countries can hamper the market growth during the forecast period.

Rising prevalence of diabetes

Increasing prevalence of diabetes across the globe is primarily driving the market growth. Diabetes has become one of the leading causes of end-stage kidney disease due to both microvascular and macrovascular complications impacting the kidneys over the long run. As more people are diagnosed with diabetes every year due to changing lifestyle habits and lack of physical activity, the risk of developing diabetic kidney disease also increases proportionately. Early detection and treatment can help slow the progression but healthcare systems need to be better prepared to handle this growing caseload.

Market Concentration and Competitive Landscape

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With improved medical care and living standards, people around the world are living longer. Longer life expectancy means the proportion of elderly population is increasing exponentially in many countries. Age is a significant risk factor for developing chronic kidney diseases including those resulting from diabetes. Older patients typically have longstanding diabetes which increases their vulnerability to kidney damage over the decades. Managing kidney health of the geriatric group is an ongoing challenge. As life expectancy increases globally, more people will live with diabetes into their old age, thus, making them prone to age-related complications like diabetic kidney disease. Healthcare systems need to gear up for the rising healthcare needs of the growing elderly diabetic population at risk of associated co-morbidities.

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One of the major challenges faced by the diabetic kidney disease market is lack of awareness about the disease among general population as well as physicians. Late diagnosis results in poor treatment outcomes. Affordability of existing treatment options is another barrier as drugs and dialysis are very costly. Rising healthcare costs can limit access to care for underprivileged patients.

Market Opportunities – Increasing diabetic patient pool driven by sedentary lifestyles

Increasing diabetic patient pool driven by sedentary lifestyles and obesity pandemic creates lucrative opportunities for market development over the forecasted period. More focus on early screening programs can help detect kidney disease beforehand. Novel drug delivery methods and new molecular entities in development promise better efficacy and convenience. Growth in healthcare investment and spending across regions like Asia Pacific and Latin America will boost the scope for affordable therapies.

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Drug Class segment is sub-segmented into angiotensin receptor blockers (ARBs), calcium channel blockers, antioxidant inflammation modulator, angiotensin-converting enzyme (ACE) inhibitors, and others. Angiotensin Receptor Blockers (ARBs) segment is estimated to hold 33.9% share of the market in 2024. ARBs are generally well-tolerated with lesser side effects as compared to other counterparts like ACE inhibitors, which positively impacts treatment compliance. These demonstrate renal protection benefits by inhibiting actions of angiotensin II receptor and reducing proteinuria, a major risk factor for progression of kidney disease. ARBs also present cardiovascular risk reduction in diabetics by controlling blood pressure and fluid overload more efficiently. Being a once daily oral dosage form, ARBs provide convenience to patients as compared to other frequent dosing options. The availability of affordable generic versions of ARBs allows wider access and adoption rates among diabetes patients with renal complications worldwide.

Insights, By Route of Administration: Ease of administration drives oral segment growth

Route of Administration segment is sub-segmented into oral and parenteral. Oral  segment is expected to hold 74.9% of the market share in 2024. Oral route enables self-administration of medications without any medical supervision or professional assistance. This promotes better compliance to treatment among kidney disease patients with diabetes. Being a chronic disease, oral administration eases lifelong therapy related challenges. It also avoids risks of complications from injections or intravenous therapies. Their stability at room temperature also facilitates storage and logistics with reduced cold chain requirements compared to parenteral products.

Insights, By Distribution Channel: Ease of access drives retail pharmacies growth

Distribution Channel segment is sub-segmented into hospital pharmacies, retail pharmacies, and online pharmacies. Retail pharmacies  segment is expected to hold 41.9% of the market share in 2024. Retail pharmacies are in close proximity across urban, semi-urban and even rural locations, allowing patients to conveniently purchase medications near their homes or workplaces. This eases fulfillment of frequent prescription refills while managing chronic kidney diseases arised due to diabetes. Being a one-stop shop for all healthcare and nutrition needs, retail outlets promote medication adherence through continued customers' visits.

Regional Insights

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North America region has been dominating the global diabetic kidney disease market over the years and is projected to hold 38.2% of the market share in 2024. The U.S. accounts for the largest share primarily due to t rising prevalence of diabetes as well as better access to healthcare and advanced treatment options in the country. The economic ability and healthcare infrastructure in the region allow for large investments in R&D which has led to the development of innovative drugs and new treatment modalities. Most of the leading pharmaceutical players have their headquarters in the U.S. and focus on drug innovation for diabetic kidney disease. This has ensured early availability and adoption of new treatment options.

The Asia Pacific region has emerged as the fastest growing market for diabetic kidney disease treatment globally. Countries like China, India and Japan are experiencing rapid economic development and growth of medical infrastructure. While Asia has a lower rate of diagnosed cases currently due to lack of screening, the prevalence of diabetes is rising sharply due to expanding urbanization and lifestyle changes. Asia Pacific accounted for over 60% of the world's diabetic population in 2019. Rising awareness, screening programs and availability of affordable generic drugs are driving the market growth. Governments are also investing in initiatives to expand health insurance coverage thus, driving the market growth.

Market Report Scope

Diabetic Kidney Disease Industry News

• On March 05, 2024, Novo Nordisk, a multinational pharmaceutical company announced the results from the kidney outcomes trial FLOW. The double-blind trial compared injectable semaglutide 1.0 mg with placebo as an adjunct to standard of care for prevention of progression of kidney impairment and risk of kidney and cardiovascular mortality in people with type 2 diabetes and chronic kidney disease (CKD). In the trial, semaglutide 1.0 mg appeared to have a safe and well-tolerated profile in line with previous semaglutide 1.0 mg trials.
• In February 2023, The European Commission approved a label extension for Kerendia (finerenone) in the European Union (EU) that includes cardiovascular (CV) outcomes from the Phase III FIGARO-DKD research. The study found that Kerendia lowered the risk of cardiovascular events in a large sample of patients with CKD stages 1-4 and T2D. Kerendia is currently recommended for the treatment of chronic kidney disease (albuminuria) in individuals with type 2 diabetes.
• In January 2023, Boehringer Ingelheim, a pharmaceutical company, and Eli Lilly and Company, a pharmaceutical company, announced that the U.S. Food and Drug Administration (FDA) had accepted a supplemental New Drug Application (sNDA) for Jardiance (empagliflozin) tablets, which are being investigated as a potential treatment to reduce the risk of kidney disease progression and cardiovascular death in adults with chronic kidney disease (CKD)
• In April 2021, AstraZeneca, a global pharmaceutical company, announced that Farxiga (dapagliflozin), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, had been approved in the U.S. by FDA to reduce the risk of sustained estimated glomerular filtration rate (eGFR) decline, end-stage kidney disease (ESKD), cardiovascular (CV) death, and heart failure hospitalization (hHF) in adults with CKD at risk of progression

*Definition: Diabetic Kidney Disease Market covers products and services used in the diagnosis and treatment of kidney disease caused by diabetes. This includes drugs for slowing the progression of kidney damage such as ACE inhibitors and SGLT2 inhibitors. It also involves products for renal replacement therapy like dialysis machines, dialyzers, vascular access products and consumables. The market covers equipment and technologies used for kidney biopsy, diagnostic tests to check kidney function and stage of disease.

Market Segmentation

•  Drug Class Insights (Revenue, USD BN, 2019 - 2031)
  • Angiotensin Receptor Blockers (ARBs)
  • Calcium Channel Blockers
  • Antioxidant Inflammation Modulator
  • Angiotensin-Converting Enzyme (ACE) Inhibitors
  • Others
•  Route of Administration Insights (Revenue, USD BN, 2019 - 2031)
  • Oral
  • Parenteral
•  Distribution Channel Insights (Revenue, USD BN, 2019 - 2031)
  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies
• Regional Insights (Revenue, USD BN, 2019 - 2031)
  • North America
    • U.S.
    • Canada
  • Latin America
    • Brazil
    • Argentina
    • Mexico
    • Rest of Latin America
  • Europe
    • Germany
    • U.K.
    • Spain
    • France
    • Italy
    • Russia
    • Rest of Europe
  • Asia Pacific
    • China
    • India
    • Japan
    • Australia
    • South Korea
    • ASEAN
    • Rest of Asia Pacific
  • Middle East
    • GCC
    • Israel
    • Rest of Middle East
  • Africa
    • South Africa
    • North Africa
    • Central Africa
• Key Players Insights
  • AstraZeneca
  • Boehringer Ingelheim
  • Janssen Pharmaceuticals
  • Bristol Myers Squibb
  • GSK
  • Novo Nordisk
  • Eli Lilly and Company
  • Merck & Co.
  • Sanofi
  • AbbVie
  • Sun Pharmaceutical Industries Ltd
  • Teva Pharmaceutical Industries Ltd 
  • Lupin 
  • Aurobindo Pharma 
  • Takeda Pharmaceutical Company Limited
  • Biogen
  • Vertex Pharmaceuticals Incorporated